Dental implant ; surface modification ; sodium hydroxide ; hydrogen bonding ; bone morphogenetic protein
Abstract
In order to activate dental implant surface for osseointegration, one of growth factor - recombinant human bone morphogenetic protein-2(rhBMP-2) coating on surface modified titanium with sodium hydroxide was designed. The physico- chemical properties of surface modified titanium and the rhBMP-2 eluting characteristic of the modified titanium were evaluated. The longer sodium hydroxide exposition time, the less eluting of rhBMP-2 on sodium hydroxide treated titanium was observed. Key words: Dental implant, surface modification, sodium hydroxide, hydrogen bonding, bone morphogenetic protein