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성인 신장이식 후 재발한 초점성 분절성 사구체경화증의 임상양상

Other Titles
 Clinical Characteristics of Focal Segmental Glomerulosclerosis Recurrence after Adult Renal Transplantation 
Authors
 주동진  ;  이정준  ;  이병모  ;  김명수  ;  허규하  ;  김수진  ;  김순일  ;  김유선 
Citation
 Journal of the Korean Society for Transplantation (대한이식학회지), Vol.24(2) : 87-92, 2010 
Journal Title
 Journal of the Korean Society for Transplantation (대한이식학회지) 
ISSN
 1598-1711 
Issue Date
2010
Keywords
Focal segmental glomerulosclerosis ; Kidney transplantation ; Risk factors ; Recurrence
Abstract
BACKGROUND: Recurrence of focal segmental glomerulosclerosis (FSGS) after kidney transplantation is a frequent and still unpredictable complication. Moreover, risk factors for recurrence have not yet been clearly identified. METHODS: We enrolled into our study 2,882 adult kidney recipients who underwent transplantation between April 1979 and April 2009. We retrospectively reviewed clinical manifestations of recurrence of FSGS. RESULTS: Among the 2,784 adult renal recipients, forty four had undergone renal transplantation for primary FSGS. Of the 44, 12 (27.3%) showed recurrent FSGS. Mean duration between transplantation and FSGS recurrence was 22.8+/-37.4 months. There were no significant differences in patient characteristics in the recurrence and non-recurrence groups. The cumulative incidence of FSGS recurrence was 13.8% within 1 year after kidney transplantation and 23.2% within 3 years. The overall graft survival rate in the recurrence group was significantly lower than that of the non-recurrence group (P=0.0018) and non-FSGS group (P=0.0001). Graft failure happened more in the recurrence group (75%) than in the non-recurrence group (37.5%, P=0.042). CONCLUSIONS: We failed to find any significant risk factors for FSGS recurrence after renal transplantation.
Files in This Item:
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DOI
10.4285/jkstn.2010.24.2.87
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myoung Soo(김명수) ORCID logo https://orcid.org/0000-0002-8975-8381
Kim, Soo Jin(김수진)
Kim, Soon Il(김순일) ORCID logo https://orcid.org/0000-0002-0783-7538
Kim, Yu Seun(김유선) ORCID logo https://orcid.org/0000-0002-5105-1567
Lee, Byung Mo(이병모)
Lee, Jung Jun(이정준)
Joo, Dong Jin(주동진) ORCID logo https://orcid.org/0000-0001-8405-1531
Huh, Kyu Ha(허규하) ORCID logo https://orcid.org/0000-0003-1364-6989
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102172
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