257 366

Cited 13 times in

A Nationwide Survey of Lymphangioleiomyomatosis in Korea: Recent Increase in Newly Diagnosed Patients

Authors
 Hye Yun Park  ;  Hae-Seong Nam  ;  Man Pyo Chung  ;  Sung Hwan Jeong  ;  Yu Jin Kim  ;  Seung-Ick Cha  ;  Young Whan Kim  ;  Jong Sun Park  ;  Soo-Taek Uh  ;  Choon-Sik Park  ;  Moo Suk Park  ;  Ji Ae Moon  ;  Kyung Soo Jung  ;  Yang Jin Jegal  ;  Dong Soon Kim  ;  Jin Woo Song  ;  Ho-Kee Yum  ;  Young Bum Park 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.25(8) : 1182-1186, 2010 
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
 1011-8934 
Issue Date
2010
MeSH
Adult ; Aged ; Early Diagnosis ; Female ; Humans ; Lung Neoplasms/diagnosis* ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/mortality ; Lymphangioleiomyomatosis/diagnosis* ; Lymphangioleiomyomatosis/diagnostic imaging ; Lymphangioleiomyomatosis/mortality ; Middle Aged ; Republic of Korea ; Respiratory Function Tests ; Survival Rate ; Tomography, X-Ray Computed
Keywords
Korea ; Lymphangioleiomyomatosis ; Registries ; Respiratory Function Tests
Abstract
In 2007, the Korean Interstitial Lung Disease Society had collected clinical data of patients who have diagnosed as Lymphangioleiomyomatosis (LAM) since 1990 through nationwide survey, which showed that LAM patients had increased sharply after 2004. The present study was performed to show the clinical features of Korean patients with LAM, and to establish the reason for the recent increase in the diagnosis. All 63 patients were women and the mean age at diagnosis was 36 yr. The most common presenting symptom was dyspnea and 8 patients had tuberous sclerosis complex. The survival rate at 5 yr after diagnosis was 84%. Compared with patients diagnosed after 2004 (n=34), the patients diagnosed before 2004 (n=29) complained with dyspnea more (P=0.016) and had lower FEV1% predicted (P=0.003), and DLco% predicted (P=0.042). The higher proportion of patients diagnosed after 2004 showed the normal chest radiography, and they were detected by routine chest CT screening (P=0.016). This study showed that clinical features of Korean patients with LAM were not different from those reported elsewhere. It is concluded that the reason for the increase of newly diagnosed patients is the result of increase in detection of the early stage LAM by the widespread use of chest CT screening.
Files in This Item:
T201003193.pdf Download
DOI
10.3346/jkms.2010.25.8.1182
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Moon, Ji Ae(문지애)
Park, Moo Suk(박무석) ORCID logo https://orcid.org/0000-0003-0820-7615
Jung, Kyung Soo(정경수) ORCID logo https://orcid.org/0000-0003-1604-8730
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102026
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links