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A Nationwide Survey of Lymphangioleiomyomatosis in Korea: Recent Increase in Newly Diagnosed Patients

DC Field Value Language
dc.contributor.author문지애-
dc.contributor.author박무석-
dc.contributor.author정경수-
dc.date.accessioned2015-04-23T17:12:28Z-
dc.date.available2015-04-23T17:12:28Z-
dc.date.issued2010-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/102026-
dc.description.abstractIn 2007, the Korean Interstitial Lung Disease Society had collected clinical data of patients who have diagnosed as Lymphangioleiomyomatosis (LAM) since 1990 through nationwide survey, which showed that LAM patients had increased sharply after 2004. The present study was performed to show the clinical features of Korean patients with LAM, and to establish the reason for the recent increase in the diagnosis. All 63 patients were women and the mean age at diagnosis was 36 yr. The most common presenting symptom was dyspnea and 8 patients had tuberous sclerosis complex. The survival rate at 5 yr after diagnosis was 84%. Compared with patients diagnosed after 2004 (n=34), the patients diagnosed before 2004 (n=29) complained with dyspnea more (P=0.016) and had lower FEV1% predicted (P=0.003), and DLco% predicted (P=0.042). The higher proportion of patients diagnosed after 2004 showed the normal chest radiography, and they were detected by routine chest CT screening (P=0.016). This study showed that clinical features of Korean patients with LAM were not different from those reported elsewhere. It is concluded that the reason for the increase of newly diagnosed patients is the result of increase in detection of the early stage LAM by the widespread use of chest CT screening.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1182~1186-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHEarly Diagnosis-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLung Neoplasms/diagnosis*-
dc.subject.MESHLung Neoplasms/diagnostic imaging-
dc.subject.MESHLung Neoplasms/mortality-
dc.subject.MESHLymphangioleiomyomatosis/diagnosis*-
dc.subject.MESHLymphangioleiomyomatosis/diagnostic imaging-
dc.subject.MESHLymphangioleiomyomatosis/mortality-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRespiratory Function Tests-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTomography, X-Ray Computed-
dc.titleA Nationwide Survey of Lymphangioleiomyomatosis in Korea: Recent Increase in Newly Diagnosed Patients-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHye Yun Park-
dc.contributor.googleauthorHae-Seong Nam-
dc.contributor.googleauthorMan Pyo Chung-
dc.contributor.googleauthorSung Hwan Jeong-
dc.contributor.googleauthorYu Jin Kim-
dc.contributor.googleauthorSeung-Ick Cha-
dc.contributor.googleauthorYoung Whan Kim-
dc.contributor.googleauthorJong Sun Park-
dc.contributor.googleauthorSoo-Taek Uh-
dc.contributor.googleauthorChoon-Sik Park-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorJi Ae Moon-
dc.contributor.googleauthorKyung Soo Jung-
dc.contributor.googleauthorYang Jin Jegal-
dc.contributor.googleauthorDong Soon Kim-
dc.contributor.googleauthorJin Woo Song-
dc.contributor.googleauthorHo-Kee Yum-
dc.contributor.googleauthorYoung Bum Park-
dc.identifier.doi10.3346/jkms.2010.25.8.1182-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01385-
dc.contributor.localIdA01457-
dc.contributor.localIdA03570-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid20676330-
dc.subject.keywordKorea-
dc.subject.keywordLymphangioleiomyomatosis-
dc.subject.keywordRegistries-
dc.subject.keywordRespiratory Function Tests-
dc.contributor.alternativeNameMoon, Ji Ae-
dc.contributor.alternativeNamePark, Moo Suk-
dc.contributor.alternativeNameJung, Kyung Soo-
dc.contributor.affiliatedAuthorMoon, Ji Ae-
dc.contributor.affiliatedAuthorPark, Moo Suk-
dc.contributor.affiliatedAuthorJung, Kyung Soo-
dc.citation.volume25-
dc.citation.number8-
dc.citation.startPage1182-
dc.citation.endPage1186-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.25(8) : 1182-1186, 2010-
dc.identifier.rimsid52667-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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