Cited 26 times in
Screening for latent tuberculosis infection in South Korean healthcare workers using a tuberculin skin test and whole blood interferon-gamma assay
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강영애 | - |
dc.contributor.author | 김세규 | - |
dc.contributor.author | 김영미 | - |
dc.contributor.author | 김영삼 | - |
dc.contributor.author | 문진욱 | - |
dc.contributor.author | 박무석 | - |
dc.contributor.author | 이경종 | - |
dc.contributor.author | 장준 | - |
dc.contributor.author | 조상래 | - |
dc.date.accessioned | 2015-04-23T17:10:16Z | - |
dc.date.available | 2015-04-23T17:10:16Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0036-5548 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101955 | - |
dc.description.abstract | This study compared the results of a tuberculin skin test (TST) and a whole-blood interferon-gamma release assay (IGRA) to screen latent tuberculosis (TB) infection (LTBI) according to risk of TB exposure in South Korea. A cross-sectional comparison of 82 healthcare workers (HCWs) was performed from June 2009 to January 2010. Participants were grouped according to their risk for TB exposure: group 1, frequent and direct contact with active TB patients (n = 35); group 2, no known history of direct contact with active TB patients (n = 47). For the TST (10-mm induration cut-off), the positive response rate was 42.9% in group 1 and 34.0% in group 2 (p = 0.42). For the IGRA, the positive response rate was 40% in group 1 and 10.6% in group 2 (p = 0.002). Results obtained from the TST and the IGRA were not in significant agreement. The working duration of HCWs in TB-related departments was the only significant risk factor for LTBI (odds ratio 1.03; p = 0.031). Further, the IGRA can more accurately discriminate LTBI compared to the TST, based on the risk of TB exposure. These results suggest that the IGRA is diagnostically useful for LTBI in South Korean HCWs. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 672~678 | - |
dc.relation.isPartOf | SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Chi-Square Distribution | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Enzyme-Linked Immunosorbent Assay/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Health Personnel* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Interferon-gamma/blood* | - |
dc.subject.MESH | Latent Tuberculosis/blood | - |
dc.subject.MESH | Latent Tuberculosis/diagnosis* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mass Screening/methods | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Statistics, Nonparametric | - |
dc.subject.MESH | Tuberculin Test/methods* | - |
dc.title | Screening for latent tuberculosis infection in South Korean healthcare workers using a tuberculin skin test and whole blood interferon-gamma assay | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Medical Research Center (임상의학연구센터) | - |
dc.contributor.googleauthor | Kyung Jong Lee | - |
dc.contributor.googleauthor | Young Ae Kang | - |
dc.contributor.googleauthor | Young Mi Kim | - |
dc.contributor.googleauthor | Sang-Nae Cho | - |
dc.contributor.googleauthor | Jin Wook Moon | - |
dc.contributor.googleauthor | Moo Suk Park | - |
dc.contributor.googleauthor | Se Kyu Kim | - |
dc.contributor.googleauthor | Joon Chang | - |
dc.contributor.googleauthor | Young Sam Kim | - |
dc.identifier.doi | 10.3109/00365548.2010.485575 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00057 | - |
dc.contributor.localId | A00602 | - |
dc.contributor.localId | A00705 | - |
dc.contributor.localId | A00707 | - |
dc.contributor.localId | A01387 | - |
dc.contributor.localId | A01457 | - |
dc.contributor.localId | A03472 | - |
dc.contributor.localId | A03824 | - |
dc.contributor.localId | A02654 | - |
dc.relation.journalcode | J02634 | - |
dc.identifier.eissn | 1651-1980 | - |
dc.identifier.pmid | 20482459 | - |
dc.identifier.url | http://informahealthcare.com/doi/abs/10.3109/00365548.2010.485575 | - |
dc.contributor.alternativeName | Kang, Young Ae | - |
dc.contributor.alternativeName | Kim, Se Kyu | - |
dc.contributor.alternativeName | Kim, Young Mi | - |
dc.contributor.alternativeName | Kim, Young Sam | - |
dc.contributor.alternativeName | Moon, Jin Wook | - |
dc.contributor.alternativeName | Park, Moo Suk | - |
dc.contributor.alternativeName | Lee, Kyung Jong | - |
dc.contributor.alternativeName | Chang, Joon | - |
dc.contributor.alternativeName | Cho, Sang Nae | - |
dc.contributor.affiliatedAuthor | Kang, Young Ae | - |
dc.contributor.affiliatedAuthor | Kim, Se Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Young Mi | - |
dc.contributor.affiliatedAuthor | Kim, Young Sam | - |
dc.contributor.affiliatedAuthor | Moon, Jin Wook | - |
dc.contributor.affiliatedAuthor | Park, Moo Suk | - |
dc.contributor.affiliatedAuthor | Chang, Joon | - |
dc.contributor.affiliatedAuthor | Cho, Sang Nae | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Jong | - |
dc.citation.volume | 42 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 672 | - |
dc.citation.endPage | 678 | - |
dc.identifier.bibliographicCitation | SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, Vol.42(9) : 672-678, 2010 | - |
dc.identifier.rimsid | 50970 | - |
dc.type.rims | ART | - |
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