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Chronological changes in the systemic manifestations of intestinal Behcet's disease and their significance in diagnosis.

Authors
 Sung Jae Shin  ;  Sang Kil Lee  ;  Tae Il Kim  ;  Jae Hee Cheon  ;  Eun Soo Kim  ;  Byung Chang Kim  ;  Sooyoung Park  ;  Won Ho Kim 
Citation
 International Journal of Colorectal Disease, Vol.25(11) : 1371-1376, 2010 
Journal Title
 International Journal of Colorectal Disease 
ISSN
 0179-1958 
Issue Date
2010
Abstract
PURPOSE: Intestinal Behçet's disease (BD) is challenging to diagnose, especially if the patient presents with typical colonoscopic findings of intestinal BD without systemic manifestations of BD. We performed this study to evaluate the systemic manifestations of BD in patients with typical colonoscopic findings of intestinal BD at the time of initial presentation and to identity the chronologic changes of these features during an extended follow-up period. METHODS: One hundred twenty-six consecutive patients who showed typical colonoscopic findings of intestinal BD at a single institution in Korea were enrolled. Clinical and endoscopic data were collected from a medical database and using a written questionnaire. Parameters including demographic characteristics and the subset type of BD at the initial and endpoints of the follow-up were analyzed. RESULTS: The mean follow-up period was 63.9 ± 50.9 months. The number of cases that satisfied the International Study Group for Behçet's Disease criteria at initial diagnosis, 19.0%, increased to 53.2% by the end of follow-up. When the Japanese criteria were used for classification, the proportion of complete and incomplete type BD increased (2.4% and 26.2% to 18.3% and 49.2%, respectively), while that of suspected and not-satisfied subtype BD decreased (22.2% and 49.2% to 19.0% and 13.5%, respectively) during the follow-up period. CONCLUSIONS: Our data suggest that patients who lack the systemic manifestations of BD could be included in the category of intestinal BD when typical intestinal lesion is identified, indicating that close examination and early treatment should be considered in such patients
Full Text
http://link.springer.com/article/10.1007%2Fs00384-010-0968-8
DOI
10.1007/s00384-010-0968-8
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
김병창(Kim, Byung Chang)
김원호(Kim, Won Ho)
김은수(Kim, Eun Soo)
김태일(Kim, Tae Il) ORCID logo https://orcid.org/0000-0003-4807-890X
박수영(Park, Soo Young)
신성재(Shin, Sung Jae)
이상길(Lee, Sang Kil) ORCID logo https://orcid.org/0000-0002-0721-0364
천재희(Cheon, Jae Hee) ORCID logo https://orcid.org/0000-0002-2282-8904
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101728
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