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Pattern of failure in bladder cancer patients treated with radical cystectomy: rationale for adjuvant radiotherapy

DC Field Value Language
dc.contributor.author김귀언-
dc.contributor.author김용배-
dc.contributor.author나군호-
dc.contributor.author양승철-
dc.contributor.author오영택-
dc.contributor.author조남훈-
dc.contributor.author조재호-
dc.contributor.author최영득-
dc.contributor.author한웅규-
dc.contributor.author홍성준-
dc.date.accessioned2015-04-23T16:57:37Z-
dc.date.available2015-04-23T16:57:37Z-
dc.date.issued2010-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101558-
dc.description.abstractThus far, the role of adjuvant radiotherapy (RT) after radical cystectomy (RC) in urinary bladder cancer patients has yet to be defined. The purpose of this study is to analyze patterns of failure, and suggest the rationale for RT. Between 1986 and 2005, a total of 259 patients treated with RC and pelvic lymph node dissection was enrolled. The age range was 27-82 yr (median, 62 yr). Node positivity increased according to tumor staging. Patients were divided into the following two groups based on pathologic analysis: organ-confined disease group (n=135) and extravesical/lymph node-positive disease group (n=80). Pelvic failures (PF) were observed in 8 (4.9%) in organ-confined disease group, and 21 (21.7%) in extravesical/lymph node-positive disease group. Five-year PF-free survival rates were 91.2% in organ-confined disease group and 68.0% in extravesical/lymph node-positive disease group. Five-year cancer-specific survival rates were 86.2% in organ-confined disease group and 53.9% in extravesical/lymph node-positive disease group. In conclusion, a relatively high PF rate was observed in extravesical lymph node-negative and lymph node-positive disease patients in this study. Adjuvant pelvic RT may be considered to reduce pelvic failures in extravesical lymph node-positive bladder cancer. Future prospective trials are required to test the clinical benefit of adjuvant RT.-
dc.description.statementOfResponsibilityopen-
dc.format.extent835~840-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHCystectomy*-
dc.subject.MESHData Interpretation, Statistical-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLymph Node Excision-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPrognosis-
dc.subject.MESHRadiotherapy, Adjuvant-
dc.subject.MESHSurvival Rate-
dc.subject.MESHUrinary Bladder/surgery-
dc.subject.MESHUrinary Bladder Neoplasms/mortality-
dc.subject.MESHUrinary Bladder Neoplasms/radiotherapy-
dc.subject.MESHUrinary Bladder Neoplasms/therapy*-
dc.titlePattern of failure in bladder cancer patients treated with radical cystectomy: rationale for adjuvant radiotherapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorYong Bae Kim-
dc.contributor.googleauthorSung Joon Hong-
dc.contributor.googleauthorSeung Cheol Yang-
dc.contributor.googleauthorJae Ho Cho-
dc.contributor.googleauthorYoung Deuk Choi-
dc.contributor.googleauthorGwi Eon Kim-
dc.contributor.googleauthorKoon Ho Rha-
dc.contributor.googleauthorWoong Kyu Han-
dc.contributor.googleauthorNam Hoon Cho-
dc.contributor.googleauthorYoung Taek Oh-
dc.identifier.doi10.3346/jkms.2010.25.6.835-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03901-
dc.contributor.localIdA00744-
dc.contributor.localIdA00321-
dc.contributor.localIdA01227-
dc.contributor.localIdA02294-
dc.contributor.localIdA03812-
dc.contributor.localIdA04111-
dc.contributor.localIdA04308-
dc.contributor.localIdA04402-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid20514302-
dc.subject.keywordPelvic Failure-
dc.subject.keywordRadical Cystectomy-
dc.subject.keywordRadiotherapy-
dc.subject.keywordAdjuvant-
dc.subject.keywordUrinary Bladder Neopla는-
dc.contributor.alternativeNameKim, Gwi Eon-
dc.contributor.alternativeNameKim, Yong Bae-
dc.contributor.alternativeNameRha, Koon Ho-
dc.contributor.alternativeNameYang, Seung Choul-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.alternativeNameCho, Nam Hoon-
dc.contributor.alternativeNameCho, Jae Ho-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameHan, Woong Kyu-
dc.contributor.alternativeNameHong, Sung Joon-
dc.contributor.affiliatedAuthorCho, Jae Ho-
dc.contributor.affiliatedAuthorKim, Yong Bae-
dc.contributor.affiliatedAuthorKim, Gwi Eon-
dc.contributor.affiliatedAuthorRha, Koon Ho-
dc.contributor.affiliatedAuthorYang, Seung Choul-
dc.contributor.affiliatedAuthorCho, Nam Hoon-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorHan, Woong Kyu-
dc.contributor.affiliatedAuthorHong, Sung Joon-
dc.citation.volume25-
dc.citation.number6-
dc.citation.startPage835-
dc.citation.endPage840-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.25(6) : 835-840, 2010-
dc.identifier.rimsid40089-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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