Cited 15 times in
Can preoperative diffusion-weighted MRI predict postoperative hepatic insufficiency after curative resection of HBV-related hepatocellular carcinoma? A pilot study
DC Field | Value | Language |
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dc.contributor.author | 김경식 | - |
dc.contributor.author | 김도영 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김승업 | - |
dc.contributor.author | 김영철 | - |
dc.contributor.author | 박영년 | - |
dc.contributor.author | 박준용 | - |
dc.contributor.author | 안상훈 | - |
dc.contributor.author | 전재윤 | - |
dc.contributor.author | 최기홍 | - |
dc.contributor.author | 최은희 | - |
dc.contributor.author | 최지수 | - |
dc.contributor.author | 최진섭 | - |
dc.contributor.author | 한광협 | - |
dc.date.accessioned | 2015-04-23T16:50:33Z | - |
dc.date.available | 2015-04-23T16:50:33Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0730-725X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101331 | - |
dc.description.abstract | Liver fibrosis determines the functional liver reserve. Several studies have reported that the apparent diffusion coefficient (ADC) values of diffusion-weighted magnetic resonance imaging (DW-MRI) can assess liver fibrosis. We investigated whether DW-MRI predicts postoperative hepatic insufficiency and liver fibrosis in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Twenty-six patients with HBV-related HCC who received preoperative DW-MRI on a 3-T MRI system were enrolled between July and December 2008. ADC values were measured twice by two observers. Three "b values" were used: 50, 400 and 800 s/mm(2). Postoperative hepatic insufficiency was defined as persistent hyperbilirubinemia (total bilirubin level >5 mg/dl for more than 5 days after surgery) or postoperative death without other causes. The mean age (21 men and 5 women) was 51.4 years. Three patients experienced postoperative hepatic insufficiency. liver stiffness measurement predicted postoperative hepatic insufficiency, advanced fibrosis (F3-4), and cirrhosis significantly [area under the receiving operator characteristic curve (AUROC)=0.942, 0.771 and 0.818, respectively, with P=.047, 0.048 and 0.006, respectively]; ADC values of DW-MRI, however, did not (AUROC=0.797, 0.648 and 0.491, respectively, with P=.100, 0.313 and 0.938, respectively). Reliability of ADC values between right and left hepatic lobes (rho=0.868 and rho=0.910 in the first and second measures of Observer A; rho=0.865 and rho=0.831 in the first and second measures of Observer B) was high and the intra- and interobserver reliability (rho=0.958 in observer A and rho=0.977 in observer B; rho=0.929 in the first measure and rho=0.978 in the second measure between the two observers) were high. All reliability was significant (P<.001). Our results suggest that DW-MRI on a 3-T MRI system is not suitable for predicting postoperative hepatic insufficiency, advanced liver fibrosis, and cirrhosis in patients with HBV-related HCC, despite significantly high reliability | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 802~811 | - |
dc.relation.isPartOf | MAGNETIC RESONANCE IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Area Under Curve | - |
dc.subject.MESH | Carcinoma, Hepatocellular/complications | - |
dc.subject.MESH | Carcinoma, Hepatocellular/surgery* | - |
dc.subject.MESH | Carcinoma, Hepatocellular/virology | - |
dc.subject.MESH | Diffusion Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hepatic Insufficiency/diagnosis* | - |
dc.subject.MESH | Hepatitis B/complications* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyperbilirubinemia/complications | - |
dc.subject.MESH | Hyperbilirubinemia/diagnosis | - |
dc.subject.MESH | Liver/pathology | - |
dc.subject.MESH | Liver/surgery | - |
dc.subject.MESH | Liver Cirrhosis/complications | - |
dc.subject.MESH | Liver Cirrhosis/diagnosis | - |
dc.subject.MESH | Liver Neoplasms/complications | - |
dc.subject.MESH | Liver Neoplasms/surgery* | - |
dc.subject.MESH | Liver Neoplasms/virology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Observer Variation | - |
dc.subject.MESH | Pilot Projects | - |
dc.subject.MESH | Postoperative Complications/diagnosis* | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Preoperative Care/methods* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Survival Analysis | - |
dc.title | Can preoperative diffusion-weighted MRI predict postoperative hepatic insufficiency after curative resection of HBV-related hepatocellular carcinoma? A pilot study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Seung Up Kim | - |
dc.contributor.googleauthor | Young Chul Kim | - |
dc.contributor.googleauthor | Ji Soo Choi | - |
dc.contributor.googleauthor | Kyung Sik Kim | - |
dc.contributor.googleauthor | Gi Hong Choi | - |
dc.contributor.googleauthor | Jin Sub Choi | - |
dc.contributor.googleauthor | Jun Yong Park | - |
dc.contributor.googleauthor | Do Young Kim | - |
dc.contributor.googleauthor | Sang Hoon Ahn | - |
dc.contributor.googleauthor | Eun Hee Choi | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.contributor.googleauthor | Chae Yoon Chon | - |
dc.contributor.googleauthor | Kwang-Hyub Han | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.identifier.doi | 10.1016/j.mri.2010.03.018 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00299 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A00654 | - |
dc.contributor.localId | A00728 | - |
dc.contributor.localId | A01563 | - |
dc.contributor.localId | A01675 | - |
dc.contributor.localId | A02226 | - |
dc.contributor.localId | A04046 | - |
dc.contributor.localId | A04163 | - |
dc.contributor.localId | A04195 | - |
dc.contributor.localId | A04199 | - |
dc.contributor.localId | A04268 | - |
dc.contributor.localId | A03544 | - |
dc.contributor.localId | A00385 | - |
dc.relation.journalcode | J02178 | - |
dc.identifier.eissn | 1873-5894 | - |
dc.identifier.pmid | 20395100 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0730725X10000810 | - |
dc.subject.keyword | Fibrosis | - |
dc.subject.keyword | Cirrhosis | - |
dc.subject.keyword | Chronic hepatitis B | - |
dc.subject.keyword | Hepatitis B virus | - |
dc.subject.keyword | Diffusion-weighted magnetic resonance imaging | - |
dc.subject.keyword | Apparent diffusion coefficient | - |
dc.subject.keyword | Liver stiffness measurement | - |
dc.subject.keyword | Transient elastography | - |
dc.subject.keyword | Hepatectomy | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.contributor.alternativeName | Kim, Kyung Sik | - |
dc.contributor.alternativeName | Kim, Do Young | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Kim, Seung Up | - |
dc.contributor.alternativeName | Kim, Young Chul | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.alternativeName | Park, Jun Yong | - |
dc.contributor.alternativeName | Ahn, Sang Hoon | - |
dc.contributor.alternativeName | Chon, Chae Yoon | - |
dc.contributor.alternativeName | Choi, Gi Hong | - |
dc.contributor.alternativeName | Choi, Eun Hee | - |
dc.contributor.alternativeName | Choi, Ji Soo | - |
dc.contributor.alternativeName | Choi, Jin Sub | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Sik | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Kim, Seung Up | - |
dc.contributor.affiliatedAuthor | Kim, Young Chul | - |
dc.contributor.affiliatedAuthor | Park, Young Nyun | - |
dc.contributor.affiliatedAuthor | Park, Jun Yong | - |
dc.contributor.affiliatedAuthor | Ahn, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Gi Hong | - |
dc.contributor.affiliatedAuthor | Choi, Eun Hee | - |
dc.contributor.affiliatedAuthor | Choi, Ji Soo | - |
dc.contributor.affiliatedAuthor | Choi, Jin Sub | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Chon, Chae Yoon | - |
dc.contributor.affiliatedAuthor | Kim, Do Young | - |
dc.citation.volume | 28 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 802 | - |
dc.citation.endPage | 811 | - |
dc.identifier.bibliographicCitation | MAGNETIC RESONANCE IMAGING, Vol.28(6) : 802-811, 2010 | - |
dc.identifier.rimsid | 49443 | - |
dc.type.rims | ART | - |
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