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Effect of baseline glomerular filtration rate on renal function following stenting for atherosclerotic renal artery stenosis

 Jae Hyun Chang  ;  Beom Seok Kim  ;  Hyung Jung Oh  ;  Tae-Hyun Yoo  ;  Shin-Wook Kang  ;  Ho Yung Lee  ;  Donghoon Choi  ;  Won-Heum Shim  ;  Kyu Hun Choi 
 Scandinavian Journal of Urology and Nephrology, Vol.44(3) : 169-174, 2010 
Journal Title
 Scandinavian Journal of Urology and Nephrology 
Issue Date
Atherosclerosis/complications ; Atherosclerosis/physiopathology* ; Atherosclerosis/surgery* ; Female ; Glomerular Filtration Rate ; Humans ; Male ; Middle Aged ; Renal Artery Obstruction/etiology ; Renal Artery Obstruction/physiopathology* ; Renal Artery Obstruction/surgery* ; Retrospective Studies ; Stents*
Predictor ; renal artery stenosis ; renal function ; stenting
OBJECTIVE: Percutaneous transluminal renal artery angioplasty and stenting (PTRAS) is one treatment option for atherosclerotic renal artery stenosis (ARAS). However, factors predicting the outcome remain controversial. This study investigated the effect of the baseline glomerular filtration rate (GFR) on renal function after PTRAS in patients with ARAS. MATERIAL AND METHODS: Patients who underwent PTRAS due to significant ARAS (luminal narrowing > or = 60%) were enrolled. The patients were divided into control (n = 57; estimated GFR (eGFR) > or = 60 ml/min/1.73 m(2)) and chronic renal failure (CRF) groups (n = 53; eGFR < 60 ml/min/1.73 m(2)), according to the baseline eGFR. RESULTS: The mean age at the time of PTRAS was 62 +/- 9 years, and the mean duration of follow-up was 50 +/- 26 months. There was a significant decrease in eGFR after PTRAS in the control group, whereas the CRF group showed no significant change in eGFR. The percentage change in eGFR was negatively correlated with the baseline eGFR (r = -0.274, p = 0.004). Multivariate linear regression revealed that only baseline eGFR predicted the change in eGFR (p = 0.032). CONCLUSIONS: PTRAS was more effective at preserving renal function in patients with moderately impaired renal function. Thus, baseline GFR may indicate the expected renal function outcome after PTRAS
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Shin Wook(강신욱) ORCID logo https://orcid.org/0000-0002-5677-4756
Kim, Beom Seok(김범석) ORCID logo https://orcid.org/0000-0002-5732-2583
Shim, Won Heum(심원흠)
Oh, Hyung Jung(오형중)
Yoo, Tae Hyun(유태현) ORCID logo https://orcid.org/0000-0002-9183-4507
Lee, Ho Yung(이호영)
Chang, Jae Hyun(장제현)
Choi, Kyu Hun(최규헌) ORCID logo https://orcid.org/0000-0003-0095-9011
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
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