Cited 5 times in
Focal eosinophilic necrosis on superparamagnetic iron oxide-enhanced MRI
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유정식 | - |
dc.contributor.author | 정재준 | - |
dc.contributor.author | 조은석 | - |
dc.contributor.author | 김기황 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김주희 | - |
dc.date.accessioned | 2015-04-23T16:36:51Z | - |
dc.date.available | 2015-04-23T16:36:51Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0361-803X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100903 | - |
dc.description.abstract | OBJECTIVE: The purpose of our study was to evaluate the usefulness of superparamagnetic iron oxide (SPIO)-enhanced MRI for distinguishing focal eosinophilic necrosis (FEN) from hepatic metastasis. MATERIALS AND METHODS: Forty-one cases of FEN in 41 patients and 40 hepatic metastases in 40 patients were analyzed on unenhanced and SPIO-enhanced T2-weighted MRI retrospectively. Depending on the extent of the remaining hyperintense area on SPIO-enhanced T2-weighted images compared with the unenhanced images, the lesions were classified into four categories--category 1, less than 25%; category 2, 25-49%; category 3, 50-75%; and category 4, more than 75%--by two independent readers. Contrast-to-noise ratio (CNR) was measured using the same region of interest on unenhanced and SPIO-enhanced T2-weighted images. In three pathologic specimens of FEN, the number of Kupffer cells was compared with that of background hepatic parenchyma. RESULTS: All metastases were classified as category 4, whereas FEN showed various distributions overall (category 1, 45.2%; category 2, 24.6%; category 3, 13.4%; category 4, 17.1%). FEN showed a decrease in CNR (from 7.9 +/- 5.8 to 6.1 +/- 5.6, p < 0.05), and metastases showed an increase in CNR (from 33.7 +/- 27.0 to 55.0 +/- 44.3, p < 0.05) after SPIO administration. In biopsy specimens, FEN had many more Kupffer cells (174.7 +/- 120.3 cells/high-power field [hpf]) than background hepatic parenchyma (23.7 +/- 9.8 cells/hpf). When using signal loss categories 1, 2, or 3 or CNR decrease, the accuracy of SPIO enhancement was 88.3%. CONCLUSION: Unlike hepatic metastases, most of the cases of FEN showed a reduction in the extent of hyperintense area or a decrease in CNR after SPIO administration on the T2-weighted images. Therefore, SPIO-enhanced T2-weighted MRI can help to differentially diagnose FEN from metastases. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1296~1302 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF ROENTGENOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Contrast Media | - |
dc.subject.MESH | Diagnosis, Differential | - |
dc.subject.MESH | Eosinophilia/diagnosis* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Ferrosoferric Oxide* | - |
dc.subject.MESH | Hepatic Encephalopathy/diagnosis* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Enhancement/methods* | - |
dc.subject.MESH | Liver Neoplasms/diagnosis* | - |
dc.subject.MESH | Liver Neoplasms/secondary* | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Necrosis/diagnosis | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Focal eosinophilic necrosis on superparamagnetic iron oxide-enhanced MRI | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Eun-Suk Cho | - |
dc.contributor.googleauthor | Jeong-Sik Yu | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.contributor.googleauthor | Jae-Joon Chung | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.identifier.doi | 10.2214/AJR.09.3208 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00951 | - |
dc.contributor.localId | A02500 | - |
dc.contributor.localId | A03712 | - |
dc.contributor.localId | A03881 | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A00426 | - |
dc.relation.journalcode | J00116 | - |
dc.identifier.eissn | 1546-3141 | - |
dc.identifier.pmid | 20410417 | - |
dc.identifier.url | http://www.ajronline.org/doi/abs/10.2214/AJR.09.3208 | - |
dc.subject.keyword | eosinophil | - |
dc.subject.keyword | liver | - |
dc.subject.keyword | MRI | - |
dc.subject.keyword | superparamagnetic iron oxide (SPIO) | - |
dc.contributor.alternativeName | Yu, Jeong Sik | - |
dc.contributor.alternativeName | Chung, Jae Joon | - |
dc.contributor.alternativeName | Cho, Eun Suk | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Yu, Jeong Sik | - |
dc.contributor.affiliatedAuthor | Chung, Jae Joon | - |
dc.contributor.affiliatedAuthor | Cho, Eun Suk | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.citation.volume | 194 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1296 | - |
dc.citation.endPage | 1302 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF ROENTGENOLOGY, Vol.194(5) : 1296-1302, 2010 | - |
dc.identifier.rimsid | 55634 | - |
dc.type.rims | ART | - |
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