Cited 9 times in
Magnetoplex based on MnFe2O4 nanocrystals for magnetic labeling and MR imaging of human mesenchymal stem cells
DC Field | Value | Language |
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dc.contributor.author | 서진석 | - |
dc.contributor.author | 양재문 | - |
dc.contributor.author | 허용민 | - |
dc.date.accessioned | 2015-04-23T16:34:20Z | - |
dc.date.available | 2015-04-23T16:34:20Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1388-0764 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100827 | - |
dc.description.abstract | For efficient labeling and tracking via magnetic resonance (MR) imaging of human mesenchymal stem cells (h-MSCs), magnetic labeling agents must be responsive to an external magnetic field. Thus, we developed ultrasensitive magnetoplex as a magnetic labeling agent composed of PEGylated MnFe2O4 nanocrystals (PMNCs) and polycationics (poly-l-lysine, PLL) for efficient labeling of the h-MSCs and monitoring of the transplanted h-MSCs for a long term. PMNCs were prepared by nanoemulsion methods composed of MnFe2O4 nanocrystals (MNCs) and amphiphilic polymers (mPEG–dodecanoic acid). The prepared PMNCs exhibited excellent biocompatibility and their polycationic complexes (PMNCs/PLL) demonstrated remarkable sensitivity compared with magnetic iron oxide nanoparticles (MION)/PLL or Ferumoxides/PLL. Furthermore, PMNCs demonstrated the potentials for novel diagnostic and therapeutic strategies with potential applications in various biomedical fields | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1275~1283 | - |
dc.relation.isPartOf | JOURNAL OF NANOPARTICLE RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Magnetoplex based on MnFe2O4 nanocrystals for magnetic labeling and MR imaging of human mesenchymal stem cells | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Jaemoon Yang | - |
dc.contributor.googleauthor | Eun-Kyung Lim | - |
dc.contributor.googleauthor | Eun-Sook Lee | - |
dc.contributor.googleauthor | Jin-Suck Suh | - |
dc.contributor.googleauthor | Seungjoo Haam | - |
dc.contributor.googleauthor | Yong-Min Huh | - |
dc.identifier.doi | 10.1007/s11051-009-9837-1 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02315 | - |
dc.contributor.localId | A01916 | - |
dc.contributor.localId | A04359 | - |
dc.relation.journalcode | J03173 | - |
dc.identifier.eissn | 1572-896X | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs11051-009-9837-1# | - |
dc.subject.keyword | Magnetic labeling | - |
dc.subject.keyword | Stem cell | - |
dc.subject.keyword | Ultrasensitive | - |
dc.subject.keyword | Monitoring | - |
dc.subject.keyword | Magnetic resonance imaging | - |
dc.subject.keyword | Nanomedicine | - |
dc.contributor.alternativeName | Suh, Jin Suck | - |
dc.contributor.alternativeName | Yang, Jae Moon | - |
dc.contributor.alternativeName | Huh, Yong Min | - |
dc.contributor.affiliatedAuthor | Yang, Jae Moon | - |
dc.contributor.affiliatedAuthor | Suh, Jin Suck | - |
dc.contributor.affiliatedAuthor | Huh, Yong Min | - |
dc.citation.volume | 12 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1275 | - |
dc.citation.endPage | 1283 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NANOPARTICLE RESEARCH, Vol.12(4) : 1275-1283, 2010 | - |
dc.identifier.rimsid | 55245 | - |
dc.type.rims | ART | - |
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