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Disseminated Mycobacterium kansasii infection associated with skin lesions: a case report and comprehensive review of the literature

 Sang Hoon Han  ;  Kyoung Min Kim  ;  Bum Sik Chin  ;  Suk Hoon Choi  ;  Han Sung Lee  ;  Myung Soo Kim  ;  Su Jin Jeong  ;  Hee Kyoung Choi  ;  Chang Oh Kim  ;  Jun Yong Choi  ;  Young Goo Song  ;  June Myung Kim 
 Journal of Korean Medical Science, Vol.25(2) : 304-308, 2010 
Journal Title
 Journal of Korean Medical Science 
Issue Date
Mycobacteruim kansasii occasionally causes disseminated infection with poor outcome in immunocompromised patients. We report the first case of disseminated M. kansasii infection associated with multiple skin lesions in a 48-yr-old male with myelodysplastic syndrome. The patient continuously had taken glucocorticoid during 21 months and had multiple skin lesions developed before 9 months without complete resolution until admission. Skin and mediastinoscopic paratracheal lymph node (LN) biopsies showed necrotizing granuloma with many acid-fast bacilli. M. kansasii was cultured from skin, sputum, and paratracheal LNs. The patient had been treated successfully with isoniazid, rifampin, ethmabutol, and clarithromycin, but died due to small bowel obstruction. Our case emphasizes that chronic skin lesions can lead to severe, disseminated M. kansasii infection in an immunocompromised patient. All available cases of disseminated M. kansasii infection in non HIV-infected patients reported since 1953 are comprehensively reviewed.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김경민(Kim, Kyung Min)
김명수(Kim, Myoung Soo)
김준명(Kim, June Myung)
김창오(Kim, Chang Oh) ORCID logo https://orcid.org/0000-0002-0773-5443
송영구(Song, Young Goo) ORCID logo https://orcid.org/0000-0002-0733-4156
이한성(Lee, Han Sung)
정수진(Jeong, Su Jin) ORCID logo https://orcid.org/0000-0003-4025-4542
진범식(Chin, Bum Sik)
최석훈(Choi, Suk Hoon)
최준용(Choi, Jun Yong) ORCID logo https://orcid.org/0000-0002-2775-3315
최희경(Choi, Hee Kyoung)
한상훈(Han, Sang Hoon) ORCID logo https://orcid.org/0000-0002-4278-5198
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