Cited 70 times in
Body size indexes for optimizing iodine dose for aortic and hepatic enhancement at multidetector CT: comparison of total body weight, lean body weight, and blood volume
DC Field | Value | Language |
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dc.contributor.author | 김명진 | - |
dc.date.accessioned | 2015-04-23T16:21:52Z | - |
dc.date.available | 2015-04-23T16:21:52Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0033-8419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100448 | - |
dc.description.abstract | PURPOSE: To evaluate and compare total body weight (TBW), lean body weight (LBW), and estimated blood volume (BV) for the adjustment of the iodine dose required for contrast material-enhanced multidetector computed tomography (CT) of the aorta and liver. MATERIALS AND METHODS: Institutional review committee approval and written informed consent were obtained. One hundred twenty patients (54 men, 66 women; mean age, 64.1 years; range, 19-88 years) who underwent multidetector CT of the upper abdomen were randomized into three groups of 40 patients each: (a) TBW group (0.6 g of iodine per kilogram of TBW), (b) LBW group (0.821 g of iodine per kilogram of LBW), and (c) BV group (men, 8.6 g of iodine per liter of BV; women, 9.9 g of iodine per liter of BV). Change in CT number between unenhanced and contrast-enhanced images per gram of iodine and maximum hepatic enhancement (MHE) adjusted for iodine dose were examined for correlation with TBW, LBW, and BV by using linear regression analysis. RESULTS: In the portal venous phase, correlation coefficients for the correlation of change in CT number per gram of iodine with TBW for the aorta and liver were -0.71 and -0.79, respectively, in the TBW group; -0.80 and -0.86, respectively, in the LBW group; and -0.68 and -0.66, respectively, in the BV group. In the liver, they were marginally higher in the LBW group than in the BV group (P = .03). Adjusted MHE remained constant at 77.9 HU +/- 10.2 (standard deviation) in the LBW group with respect to TBW, but it increased in the TBW (r = 0.80, P < .001) and BV (r = 0.70, P < .001) groups as TBW increased. CONCLUSION: When LBW, rather than TBW or BV, is used, the iodine dose required to achieve consistent hepatic enhancement may be estimated more precisely and with reduced patient-to-patient variability | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 163~169 | - |
dc.relation.isPartOf | RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | AorticDiseases/diagnostic imaging* | - |
dc.subject.MESH | BloodVolume* | - |
dc.subject.MESH | BodyWeight* | - |
dc.subject.MESH | Contrast Media/administration & dosage* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Iohexol/administration & dosage* | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Liver Diseases/diagnostic imaging* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Software | - |
dc.subject.MESH | Tomography, X-Ray Computed/methods* | - |
dc.title | Body size indexes for optimizing iodine dose for aortic and hepatic enhancement at multidetector CT: comparison of total body weight, lean body weight, and blood volume | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Hiroshi Kondo | - |
dc.contributor.googleauthor | Masayuki Kanematsu | - |
dc.contributor.googleauthor | Satoshi Goshima | - |
dc.contributor.googleauthor | Yuhei Tomita | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Noriyuki Moriyama | - |
dc.contributor.googleauthor | Minoru Onozuka | - |
dc.contributor.googleauthor | Yoshimune Shiratori | - |
dc.contributor.googleauthor | Kyongtae T. Bae | - |
dc.identifier.doi | 10.1148/radiol.09090369 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00426 | - |
dc.relation.journalcode | J02596 | - |
dc.identifier.eissn | 1527-1315 | - |
dc.identifier.pmid | 20019137 | - |
dc.identifier.url | http://pubs.rsna.org/doi/full/10.1148/radiol.09090369?pubCode=cgi | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.citation.volume | 254 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 163 | - |
dc.citation.endPage | 169 | - |
dc.identifier.bibliographicCitation | RADIOLOGY, Vol.254(1) : 163-169, 2010 | - |
dc.identifier.rimsid | 36496 | - |
dc.type.rims | ART | - |
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