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백내장 수술 전후 0.05% 사이클로스포린 점안이 눈물막 및각막수차에 미치는 영향

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dc.contributor.author김응권-
dc.contributor.author김태임-
dc.contributor.author김홍석-
dc.contributor.author서경률-
dc.contributor.author윤상철-
dc.contributor.author이형근-
dc.contributor.author정지원-
dc.date.accessioned2015-01-06T17:31:19Z-
dc.date.available2015-01-06T17:31:19Z-
dc.date.issued2014-
dc.identifier.issn0378-6471-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100135-
dc.description.abstractPurpose: To evaluate the efficacy of 0.05% cyclosporine A on tear film parameters and corneal aberration after cataract surgery. Methods: Patients who underwent cataract surgery were divided into 2 groups. Patients in Group I (23 eyes) were treated with cyclosporine A from 1 week before surgery to 3 months after surgery. Patients in Group II (24 eyes) underwent surgery without cyclosporine treatment. Tear film break-up time (BUT), Schirmer’s test I, Oxford scheme, Ocular surface disease index (OSDI), and corneal aberrations were evaluated before surgery and at 1 and 3 months after surgery. Results: In Group I, BUT was significantly improved at 3 months (p = 0.026) after surgery compared with the preoperative value. OSDI decreased significantly at 1 (p = 0.033) and 3 months (p = 0.003) after surgery compared with the preoperative value. However, there were no significant differences between preoperative and postoperative values of BUT and OSDI in Group II. Schirmer’s test results and the Oxford scheme were not significantly changed in either group. Preoperative root mean square (RMS) total values were not different between the 2 groups, but was different at postoperative 3 months (p = 0.015). Group I had a significantly lower value for total RMS than Group II. In Group I, Coma 7 (Z3-1) (p = 0.018) and spherical aberration (Z4 0) (p =0.031) were significantly decreased after surgery. In Group II, Trefoil 6 (Z3-3) (p = 0.033) was significantly increased after surgery. Conclusions: 0.05% cyclosporine A may be effective for improving dry eye syndrome and corneal aberration after cataract surgery.-
dc.description.statementOfResponsibilityopen-
dc.format.extent978~983-
dc.relation.isPartOfJOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title백내장 수술 전후 0.05% 사이클로스포린 점안이 눈물막 및각막수차에 미치는 영향-
dc.title.alternativeEffect of Cyclosporin A on Tear Film and Corneal Aberration after Cataract Surgery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthor전제훈-
dc.contributor.googleauthor김홍석-
dc.contributor.googleauthor정지원-
dc.contributor.googleauthor윤상철-
dc.contributor.googleauthor서경률-
dc.contributor.googleauthor이형근-
dc.contributor.googleauthor김응권-
dc.contributor.googleauthor김태임-
dc.identifier.doi10.3341/jkos.2014.55.7.978-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00831-
dc.contributor.localIdA01080-
dc.contributor.localIdA01193-
dc.contributor.localIdA01870-
dc.contributor.localIdA02560-
dc.contributor.localIdA03303-
dc.contributor.localIdA03736-
dc.relation.journalcodeJ01838-
dc.identifier.eissn2092-9374-
dc.subject.keywordCataract surgery-
dc.subject.keywordCorneal aberration-
dc.subject.keywordCyclosporin-
dc.subject.keywordDry eye-
dc.contributor.alternativeNameKim, Eung Kweon-
dc.contributor.alternativeNameKim, Tae Im-
dc.contributor.alternativeNameKim, Hong Seok-
dc.contributor.alternativeNameSeo, Kyuong Yul-
dc.contributor.alternativeNameYoon, Sang Chul-
dc.contributor.alternativeNameLee, Hyung Keun-
dc.contributor.alternativeNameJung, Ji Won-
dc.contributor.affiliatedAuthorKim, Eung Kweon-
dc.contributor.affiliatedAuthorKim, Tae Im-
dc.contributor.affiliatedAuthorKim, Hong Seok-
dc.contributor.affiliatedAuthorSeo, Kyuong Yul-
dc.contributor.affiliatedAuthorYoon, Sang Chul-
dc.contributor.affiliatedAuthorLee, Hyung Keun-
dc.contributor.affiliatedAuthorJung, Ji Won-
dc.citation.volume55-
dc.citation.number7-
dc.citation.startPage978-
dc.citation.endPage983-
dc.identifier.bibliographicCitationJOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, Vol.55(7) : 978-983, 2014-
dc.identifier.rimsid50533-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Humanities and Social Sciences (인문사회의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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