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Graft Survival After Video-assisted Minilaparotomy Living-donor Nephrectomy or Conventional Open Nephrectomy: Do Left and Right Allografts Differ?

Authors
 Young Eun Yoon  ;  Woong Kyu Han  ;  Kyung Hwa Choi  ;  Seung Choul Yang  ;  Yu Seun Kim  ;  Dae Ryong Kang  ;  Kyu Ha Huh  ;  Myoung Soo Kim  ;  Soon Il Kim  ;  Dong Jin Joo 
Citation
 UROLOGY, Vol.84(4) : 832-837, 2014 
Journal Title
UROLOGY
ISSN
 0090-4295 
Issue Date
2014
MeSH
Adult ; Female ; Graft Survival* ; Humans ; Laparotomy/methods* ; Living Donors ; Male ; Nephrectomy/methods* ; Retrospective Studies ; Time Factors ; Treatment Failure ; Video-Assisted Surgery*
Abstract
OBJECTIVE:
To examine the effect of the side of the allograft (left vs right) on early graft failure and long-term graft survival rates after conventional open living-donor nephrectomy (OLDN) or video-assisted minilaparotomy living-donor nephrectomy (VLDN).
MATERIALS AND METHODS:
We evaluated 2704 living-donor transplantations using OLDN or VLDN between 1991 and 2011 at a single institution. For analysis, the entire period was divided into "era 1" (1991-1997), when OLDN was prevalent; "era 2" (1998-2004), when both OLDN and VLDN were conducted; and "era 3" (2005-2011), when VLDN became prevalent.
RESULTS:
There were 822, 650, and 685 transplantations analyzed in eras 1, 2, and 3, respectively. There were no differences in causes of early graft failure between left and right allografts in any era. The right allograft survival rate in eras 1 and 2 was slightly lower than the left allograft survival rate. In era 2, during which both OLDN and VLDN were conducted, Kaplan-Meier analysis showed lower right allograft survival rate for OLDN. However, the long-term survival rates of the left and right VLDN grafts did not differ.
CONCLUSION:
Right OLDN allografts demonstrated worse long-term survival rate than left OLDN allografts, but the right and left VLDN allografts had similar long-term survival rate. VLDN appears to be an appropriate treatment option when right donor nephrectomy is desired.
Full Text
http://www.sciencedirect.com/science/article/pii/S0090429514006712
DOI
10.1016/j.urology.2014.06.028
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myoung Soo(김명수) ORCID logo https://orcid.org/0000-0002-8975-8381
Kim, Soon Il(김순일) ORCID logo https://orcid.org/0000-0002-0783-7538
Kim, Yu Seun(김유선) ORCID logo https://orcid.org/0000-0002-5105-1567
Yang, Seung Choul(양승철)
Yoon, Young Eun(윤영은)
Joo, Dong Jin(주동진) ORCID logo https://orcid.org/0000-0001-8405-1531
Choi, Kyung Hwa(최경화)
Han, Woong Kyu(한웅규) ORCID logo https://orcid.org/0000-0002-2527-4046
Huh, Kyu Ha(허규하) ORCID logo https://orcid.org/0000-0003-1364-6989
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100050
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