Browsing by Yonsei Author : Kim, Hyun Seok

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Name:
Kim, Hyun Seok [김현석]
orcid http://orcid.org/0000-0003-4498-8690
Department :
College of Medicine (의과대학) - BioMedical Science Institute (의생명과학부)
Scopus ID :
Scopus (55902657000)

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Issue DateTitleJournal Title
2023Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy THERANOSTICS
2022Selective cytotoxicity of a novel mitochondrial complex I inhibitor, YK-135, against EMT-subtype gastric cancer cell lines due to impaired glycolytic capacity BMB REPORTS
2022WNK3 inhibition elicits antitumor immunity by suppressing PD-L1 expression on tumor cells and activating T-cell function EXPERIMENTAL AND MOLECULAR MEDICINE
2022Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells CANCER COMMUNICATIONS
2022Gold(I)-Catalyzed Intramolecular Hydrothiophenylation of N-Thiophen-3-yl Alkynylamides for Accessing Thieno[3,2-b]pyridine-5(4H)-ones: Development of F-Actin Specific Fluorescent ProbesJOURNAL OF ORGANIC CHEMISTRY
2022Establishment of reference standards for multifaceted mosaic variant analysis SCIENTIFIC DATA
2021Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling SCIENTIFIC REPORTS
2020Cross-species oncogenic signatures of breast cancer in canine mammary tumors NATURE COMMUNICATIONS
2020Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities NATURE COMMUNICATIONS
2020Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer CANCERS
2020High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen SCIENTIFIC DATA
2019A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action DiscoveryCell Chemical Biology
2019Regulation of La/SSB-dependent viral gene expression by pre-tRNA 3' trailer-derived tRNA fragments NUCLEIC ACIDS RESEARCH
2018Selective Cytotoxicity of the NAMPT Inhibitor FK866 Toward Gastric Cancer Cells with Markers of the Epithelial-Mesenchymal Transition, Due to Loss of NAPRTGASTROENTEROLOGY
2018A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells SCIENTIFIC REPORTS
2018Chemistry-First Approach for Nomination of Personalized Treatment in Lung CancerCELL
2017Somatic mutation driven codon transition bias in human cancer SCIENTIFIC REPORTS
2017Identification of Pharmacologically Tractable Protein Complexes in Cancer Using the R-Based Network Clustering and Visualization Program MCODER BIOMED RESEARCH INTERNATIONAL
2016Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer. BIOINFORMATICS
2016Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating BiomarkerCANCER PREVENTION RESEARCH
2015A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression MOLECULAR SYSTEMS BIOLOGY
2015AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell SurvivalMOLECULAR AND CELLULAR BIOLOGY
2015Meta-Analysis of Large-Scale Toxicogenomic Data Finds Neuronal Regeneration Related Protein and Cathepsin D to Be Novel Biomarkers of Drug-Induced Toxicity PLOS ONE
2015Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer Medicine YONSEI MEDICAL JOURNAL
2015Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B NATURE CHEMICAL BIOLOGY
2014Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens NUCLEIC ACIDS RESEARCH
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