Cited 6 times in
Prediction of Survival by Tumor Area on Endosonography after Definitive Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of the Esophagus
DC Field | Value | Language |
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dc.contributor.author | 박준철 | - |
dc.contributor.author | 송미경 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 심충남 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 이혁 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 정현수 | - |
dc.date.accessioned | 2015-01-06T17:25:40Z | - |
dc.date.available | 2015-01-06T17:25:40Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0012-2823 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99959 | - |
dc.description.abstract | Background: Definitive chemoradiotherapy (CRT) is a reasonable approach for patients with locally advanced esophageal cancer who are not surgical candidates. This study was performed to investigate whether endosonography (EUS) assessment of tumor area response is a useful prognostic marker in patients with squamous cell carcinoma (SCC) of the esophagus who receive definitive CRT. Methods: A total of 33 patients who received definitive CRT for locally advanced esophageal SCC were enrolled. The maximal transverse cross-sectional area of the tumor was measured before and after definitive therapy. EUS response was defined as a ≥50% reduction of the tumor area after definitive CRT. Results: Based on EUS evaluation, there were 20 nonresponders (60.6%) and 13 responders (39.4%). The median progression-free survival (PFS) was significantly longer in EUS responders than EUS nonresponders (p = 0.005). However, there was no statistical significance in overall survival according to EUS response (p = 0.120). During multivariate analysis, EUS response to definitive CRT was the only significant factor associated with PFS (p = 0.045), whereas EUS response to definitive CRT was not associated with overall survival (p = 0.221). Conclusions: A reduction of the maximal cross-sectional tumor area measured by EUS correlates with a superior prognosis in patients with locally advanced SCC of the esophagus after definitive CRT. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 98~107 | - |
dc.relation.isPartOf | DIGESTION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Carcinoma, Squamous Cell/diagnostic imaging* | - |
dc.subject.MESH | Carcinoma, Squamous Cell/mortality* | - |
dc.subject.MESH | Carcinoma, Squamous Cell/therapy | - |
dc.subject.MESH | Chemoradiotherapy | - |
dc.subject.MESH | Endosonography* | - |
dc.subject.MESH | Esophageal Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Esophageal Neoplasms/mortality* | - |
dc.subject.MESH | Esophageal Neoplasms/therapy | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Prediction of Survival by Tumor Area on Endosonography after Definitive Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of the Esophagus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Yonsei Biomedical Research Center (연세의생명연구원) | - |
dc.contributor.googleauthor | Shim C.N. | - |
dc.contributor.googleauthor | Song M.K. | - |
dc.contributor.googleauthor | Lee H.S. | - |
dc.contributor.googleauthor | Chung H. | - |
dc.contributor.googleauthor | Lee H. | - |
dc.contributor.googleauthor | Shin S.K. | - |
dc.contributor.googleauthor | Lee S.K. | - |
dc.contributor.googleauthor | Lee Y.C. | - |
dc.contributor.googleauthor | Park J.C. | - |
dc.identifier.doi | 10.1159/000365073 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A02020 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02214 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A03285 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J00734 | - |
dc.identifier.eissn | 1421-9867 | - |
dc.identifier.pmid | 25196528 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/365073 | - |
dc.subject.keyword | Esophageal cancer | - |
dc.subject.keyword | Endosonography | - |
dc.subject.keyword | Tumor area | - |
dc.subject.keyword | Definitive chemoradiotherapy | - |
dc.subject.keyword | Progression-free survival | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Song, Mi Kyung | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Shim, Choong Nam | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Lee, Hyuk | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Chung, Hyun Soo | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Song, Mi Kyung | - |
dc.contributor.affiliatedAuthor | Shin, Sung Kwan | - |
dc.contributor.affiliatedAuthor | Shim, Choong Nam | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Lee, Hyuk | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 90 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 98 | - |
dc.citation.endPage | 107 | - |
dc.identifier.bibliographicCitation | DIGESTION, Vol.90(2) : 98-107, 2014 | - |
dc.identifier.rimsid | 53913 | - |
dc.type.rims | ART | - |
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