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Impact of psychological and cancer-related factors on HRQoL for Korean childhood cancer survivors

 Myung Ah Rhee  ;  Kyong Mee Chung  ;  Yuri Lee  ;  Hana K. Choi  ;  Jung Woo Han  ;  Hyo Sun Kim  ;  Sun Hee Kim  ;  Yoon Jung Shin  ;  Chuhl Joo Lyu 
 Quality of Life Research, Vol.23(9) : 2603-2612, 2014 
Journal Title
 Quality of Life Research 
Issue Date
Adolescent ; Analysis of Variance ; Case-Control Studies ; Checklist ; Child ; Female ; Health Status* ; Humans ; Male ; Mental Disorders ; Neoplasms*/psychology ; Parents/psychology ; Quality of Life*/psychology ; Republic of Korea ; Self Concept ; Surveys and Questionnaires ; Survivors/psychology*
Childhood cancer ; Survivors ; Health-related quality of life ; Self-concept
PURPOSE: The purposes of this study were (1) to compare health-related quality of life (HRQoL) between Korean childhood cancer survivors and healthy controls and (2) to examine the impact of demographic, diagnosis/treatment, and psychological variables on physical and psychosocial health in survivors. METHODS: The HRQoL (PedsQL), Self-Concept Inventory, and Child Behavior Checklist were administered to childhood cancer survivors, age/gender-matched healthy counterparts, and their parents. Independent-samples t tests and hierarchical multiple regression analyses were conducted. RESULTS: Compared with healthy controls, childhood cancer survivors reported significantly lower scores across physical and psychosocial HRQoL. For survivors, demographic, diagnosis/treatment, current health status, and psychological variables explained more than 50 % of the variance in both subscales of HRQoL. Especially, self-concept, a psychological variable, explained a significant portion of the variance in physical and psychosocial HRQoL after controlling for cancer-related factors. Several cancer-related factors including time since treatment completion, having a history of allogeneic hematopoietic stem cell transplantation, multiple treatment modalities, and suffering from severe late effects also associated with specific dimension of HRQoL. CONCLUSIONS: Childhood cancer survivors do experience lower level of QoL and psychological factors, especially self-concept, should be considered when supporting the well-being of childhood cancer survivors.
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1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyo Sun(김효선)
Lyu, Chuhl Joo(유철주) ORCID logo https://orcid.org/0000-0001-7124-7818
Han, Jung Woo(한정우) ORCID logo https://orcid.org/0000-0001-8936-1205
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