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Effect of Follow-Up Endoscopy on the Outcomes of Patients with Inflammatory Bowel Disease

Authors
 Duk Hwan Kim  ;  Soo Jung Park  ;  Jae Jun Park  ;  Young Hoon Yun  ;  Sung Pil Hong  ;  Tae Il Kim  ;  Won Ho Kim  ;  Jae Hee Cheon 
Citation
 DIGESTIVE DISEASES AND SCIENCES, Vol.59(10) : 2514-2522, 2014 
Journal Title
 DIGESTIVE DISEASES AND SCIENCES 
ISSN
 0163-2116 
Issue Date
2014
MeSH
Adolescent ; Adult ; Child ; Endoscopy* ; Female ; Hospitalization ; Humans ; Inflammatory Bowel Diseases/pathology* ; Inflammatory Bowel Diseases/therapy* ; Male ; Middle Aged ; Risk Factors ; Treatment Outcome ; Young Adult
Keywords
Inflammatory bowel disease ; Crohn’s disease ; Ulcerative colitis ; Colonoscopy ; Sigmoidoscopy
Abstract
BACKGROUND: Little is known about the role of follow-up endoscopy in patients with inflammatory bowel disease (IBD). AIM: The present study aimed to evaluate whether repeated endoscopies would be beneficial in improving outcomes of patients with IBD. METHODS: Patients who had been initially confirmed to have IBD at two tertiary hospitals in Korea were regularly followed and included in this study. The clinical impact as assessed by the presence or absence of a change in management after endoscopy and cumulative hospitalization rate was compared between two groups classified according to the presence or absence of indications. RESULTS: A total of 188 patients with IBD were enrolled [69 patients with Crohn's disease (CD) and 119 with ulcerative colitis (UC)]. Of these patients, 130 underwent follow-up endoscopy (48 with CD and 82 with UC). The rate of management change was significantly higher in the group with indications for follow-up endoscopy (p = 0.001 in CD and <0.001 in UC). The presence of any indications for follow-up endoscopy was found to be a significant predictor of hospitalization risk in patients with UC (p = 0.015), but not in those with CD. However, there was no significant difference in cumulative hospitalization hazard with respect to treatment change in patients without any endoscopic indications (p = 0.561 in CD and 0.423 in UC). CONCLUSIONS: Follow-up endoscopy might not have a significant impact on the overall clinical course and outcomes in patients with IBD. However, the presence of endoscopic indications predicts a poor clinical outcome in UC.
Full Text
http://link.springer.com/article/10.1007%2Fs10620-014-3197-0
DOI
10.1007/s10620-014-3197-0
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Duk Hwan(김덕환)
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
Kim, Tae Il(김태일) ORCID logo https://orcid.org/0000-0003-4807-890X
Park, Soo Jung(박수정)
Park, Jae Jun(박재준)
Youn, Young Hoon(윤영훈) ORCID logo https://orcid.org/0000-0002-0071-229X
Cheon, Jae Hee(천재희) ORCID logo https://orcid.org/0000-0002-2282-8904
Hong, Sung Pil(홍성필)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99830
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