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Epilepsy Surgery in Pediatric Intractable Epilepsy with Destructive Encephalopathy

 So Young Park  ;  Hye Eun Kwon  ;  Heung Dong Kim  ;  Dong Seok Kim  ;  Joon Soo Lee  ;  Hoon-Chul Kang 
 Journal of Epilepsy Research, Vol.3(2) : 48-53, 2013 
Journal Title
 Journal of Epilepsy Research 
Issue Date
Destructive encephalopathy ; Epilepsy surgery ; Intractable epilepsy
BACKGROUND AND PURPOSE: The aim of the current study is to review the clinical features, surgery outcomes and parental satisfaction of children with destructive encephalopathy who underwent epilepsy surgery due to medically intractable seizures. METHODS: 48 patients who underwent epilepsy surgery from October 2003 to August 2011 at Severance Children's Hospital have been reviewed. The survey was conducted for functional outcomes and parental satisfaction at least 1 year after the surgery. RESULTS: Epileptic encephalopathy including Lennox-Gastaut syndrome and infantile spasms was more prevalent than symptomatic focal epilepsy. Hypoxic ischemic injury accounted for most of the underlying etiology of the destructive encephalpathy, followed by central nervous system infection and head trauma. 27 patients (56.3%) underwent resective surgery and 21 patients (43.7%) underwent palliative surgery. 16 patients (33.3%) achieved seizure free and 27 parents (87.5%) reported satisfaction with the outcome of their children's epilepsy surgery. In addition, 14 parents (77.8 %) whose children were not seizure free reported satisfaction with their children's improvement in cognitive and behavior issues. CONCLUSIONS: Epilepsy surgery in destructive encephalopathy was effective for controlling seizures. Parents reported satisfaction not only with the surgical outcomes, but also with improvement of cognitive and behavior issues.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Hoon Chul(강훈철) ORCID logo https://orcid.org/0000-0002-3659-8847
Kwon, Hye Eun(권혜은)
Kim, Dong Seok(김동석)
Kim, Heung Dong(김흥동) ORCID logo https://orcid.org/0000-0002-8031-7336
Park, So Young(박소영)
Lee, Joon Soo(이준수) ORCID logo https://orcid.org/0000-0001-9036-9343
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