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The clinical features and optimal treatment of anorectal malignant melanoma

Authors
 Soomin Nam  ;  Chang Woo Kim  ;  Se Jin Baek  ;  Hyuk Hur  ;  Byung Soh Min  ;  Seung Hyuk Baik  ;  Nam Kyu Kim 
Citation
 ANNALS OF SURGICAL TREATMENT AND RESEARCH, Vol.87(3) : 113-117, 2014 
Journal Title
 ANNALS OF SURGICAL TREATMENT AND RESEARCH 
ISSN
 2288-6575 
Issue Date
2014
Keywords
Anal neoplasms ; Melanoma ; Skin neoplasms ; Surgery ; Wide local excision
Abstract
Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.
Files in This Item:
T201403015.pdf Download
DOI
10.4174/astr.2014.87.3.113
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Kyu(김남규) ORCID logo https://orcid.org/0000-0003-0639-5632
Kim, Chang Woo(김창우)
Min, Byung Soh(민병소) ORCID logo https://orcid.org/0000-0003-0180-8565
Baek, Se Jin(백세진)
Baik, Seung Hyuk(백승혁) ORCID logo https://orcid.org/0000-0003-4183-2332
Hur, Hyuk(허혁) ORCID logo https://orcid.org/0000-0002-9864-7229
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99672
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