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The Impact of Obesity on Subclinical Coronary Atherosclerosis According to the Risk of Cardiovascular Disease

DC FieldValueLanguage
dc.contributor.author조인정-
dc.contributor.author홍그루-
dc.contributor.author신상훈-
dc.contributor.author심지영-
dc.contributor.author장혁재-
dc.contributor.author정남식-
dc.contributor.author성지민-
dc.date.accessioned2015-01-06T17:09:21Z-
dc.date.available2015-01-06T17:09:21Z-
dc.date.issued2014-
dc.identifier.issn1930-7381-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99440-
dc.description.abstractOBJECTIVE: To evaluate whether the association of obesity with coronary atherosclerosis depends on the risk of cardiovascular disease (CVD). METHODS: A total of 1,406 asymptomatic Korean adults underwent both cardiac and abdominal multislice computed tomography (MSCT) as part of a routine health check-up. Obesity was measured using body mass index (BMI), waist circumference (WC), and MSCT-derived area/ratio of visceral and subcutaneous fat. The burden of CVD risk was assessed by the Framingham risk equation. RESULTS: In the low-risk group for CVD, obesity measurements (standardized odds ratio, 95% confidence interval) of BMI (1.406, 1.197-1.652), WC (1.707, 1.434-2.032), visceral fat area (1.700, 1.438-2.009), and visceral-to-subcutaneous fat ratio (1.620, 1.379-1.903) were associated with the presence of coronary calcification after adjusting for traditional CVD risks. But in the moderate-to-high risk group, the associations were attenuated. For additional adjustments of obesity measurements, in the low-risk group, WC (1.717, 1.172-2.514) and visceral-to-subcutaneous fat ratio (1.400, 1.029-1.904) were independent determinants of coronary calcification. CONCLUSIONS: Obesity is differentially associated with subclinical coronary atherosclerosis, according to the burden of CVD risk. In low-risk adults, the relative distribution of abdominal fat, as well as whole body fat, is important to coronary atherosclerosis.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1762~1768-
dc.relation.isPartOfOBESITY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAbdominal Fat/diagnostic imaging-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHBody Mass Index-
dc.subject.MESHCardiovascular Diseases/diagnosis*-
dc.subject.MESHCardiovascular Diseases/diagnostic imaging-
dc.subject.MESHCardiovascular Diseases/epidemiology*-
dc.subject.MESHCoronary Artery Disease/diagnosis*-
dc.subject.MESHCoronary Artery Disease/epidemiology*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultidetector Computed Tomography-
dc.subject.MESHObesity/complications*-
dc.subject.MESHObesity/epidemiology*-
dc.subject.MESHRisk-
dc.titleThe Impact of Obesity on Subclinical Coronary Atherosclerosis According to the Risk of Cardiovascular Disease-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSeung-Yul Lee-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorJimin Sung-
dc.contributor.googleauthorKwang Joon Kim-
dc.contributor.googleauthorSanghoon Shin-
dc.contributor.googleauthorIn-Jeong Cho-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorGeu-Ru Hong-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1002/oby.20760-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03892-
dc.contributor.localIdA04386-
dc.contributor.localIdA02107-
dc.contributor.localIdA02213-
dc.contributor.localIdA03490-
dc.contributor.localIdA03585-
dc.contributor.localIdA01955-
dc.relation.journalcodeJ02404-
dc.identifier.eissn1930-739X-
dc.identifier.pmid24719352-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/oby.20760/abstract-
dc.contributor.alternativeNameCho, In Jeong-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.alternativeNameShin, Sang Hoon-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameSung, Ji Min-
dc.contributor.affiliatedAuthorCho, In Jeong-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.contributor.affiliatedAuthorShin, Sang Hoon-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorSung, Ji Min-
dc.rights.accessRightsfree-
dc.citation.volume22-
dc.citation.number7-
dc.citation.startPage1762-
dc.citation.endPage1768-
dc.identifier.bibliographicCitationOBESITY, Vol.22(7) : 1762-1768, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Yonsei Cardiovascular Research Institute (심혈관연구소) > 1. Journal Papers

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