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미세표면분석 기법을 이용한 미용 콘택트렌즈와 일반 콘택트렌즈의표면거칠기와 세균부착성 비교

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dc.contributor.author김응권-
dc.contributor.author이형근-
dc.date.accessioned2015-01-06T17:05:24Z-
dc.date.available2015-01-06T17:05:24Z-
dc.date.issued2014-
dc.identifier.issn0378-6471-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99329-
dc.description.abstractPurpose: To determine the surface roughness of cosmetic and conventional contact lenses (CLs) and their susceptibility to bacterialadhesion. Methods: Concave surface roughness of cosmetic and conventional hydrogel (Etafilcon A) CLs was measured by atomic forcemicroscopy (AFM) and scanning electron microscopy (SEM). In particular, the surface of the color tinted area of cosmetic CLswas measured. CLs were immersed into a bacterial solution of Pseudomonas aeruginosa for 1, 12, or 24 hours and culture of P. aeruginosa that had adhered to the CLs was performed. Results: Concave surface roughness of cosmetic CLs significantly increased compared with conventional CLs by AFM (p < 0.05). Bacterial colony formation of P. aeruginosa adhering to cosmetic CLs within one hour significantly increased compared with conventionalCLs (p = 0.047). Adhesions of P. aeruginosa to CLs within one hour was found to correlate significantly with the surface roughness of CL(r > 0.9, p < 0.05). By SEM, P. aeruginosa had adhered to the color-tinted area more than to the non-color-tinted area of cosmetic CLs. Conclusions: Surface of cosmetic CLs was significantly rougher and initial adhesion of bacteria was higher to cosmetic CLs thanto conventional CLs. In particular, an increased number of bacteria was found to be adhered to the color-tinted area of cosmeticCLs. Initial bacterial adhesion is important because it is the first stage of bacterial attachment process to any surface. After then,the adherent bacteria can progress to form a biofilm. Increased surface roughness of CLs contributes to opportunities for the CLto come into contact with bacteria, and thus, initial bacterial adhesion increases. In this study, it is clear that cosmetic CLs aremore vulnerable to bacterial adhesion. To avoid serious complications, such as bacterial keratitis, the manufacturing process forsmoothing and treating the surface in order to inhibit bacterial adhesion should be developed in the future.-
dc.description.statementOfResponsibilityopen-
dc.format.extent646~655-
dc.relation.isPartOfJOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBacterial Adhesion*/drug effects-
dc.subject.MESHBacterial Adhesion*/physiology-
dc.subject.MESHBeauty Culture-
dc.subject.MESHBiofilms/drug effects-
dc.subject.MESHBiofilms/growth & development-
dc.subject.MESHColony Count, Microbial-
dc.subject.MESHContact Lenses, Hydrophilic/microbiology*-
dc.subject.MESHDisinfectants/pharmacology-
dc.subject.MESHHumans-
dc.subject.MESHMicroscopy, Atomic Force-
dc.subject.MESHMicroscopy, Electron, Scanning-
dc.subject.MESHOphthalmic Solutions/pharmacology-
dc.subject.MESHPseudomonas aeruginosa/physiology-
dc.subject.MESHStaphylococcus aureus/physiology-
dc.subject.MESHSurface Properties*-
dc.title미세표면분석 기법을 이용한 미용 콘택트렌즈와 일반 콘택트렌즈의표면거칠기와 세균부착성 비교-
dc.title.alternativeComparison of Surface Roughness and Bacterial Adhesion between Cosmetic Contact Lenses and Conventional Contact Lenses-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthor지용우-
dc.contributor.googleauthor홍순호-
dc.contributor.googleauthor정동룡-
dc.contributor.googleauthor김응권-
dc.contributor.googleauthor이형근-
dc.identifier.doi10.3341/jkos.2014.55.5.646-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00831-
dc.contributor.localIdA03303-
dc.relation.journalcodeJ01838-
dc.identifier.eissn2092-9374-
dc.identifier.pmid25536530-
dc.subject.keywordAtomic force microscope-
dc.subject.keywordBacterial adhesion-
dc.subject.keywordCosmetic contact lens-
dc.subject.keywordPseudomonas aeruginosa-
dc.subject.keywordSurface roughness-
dc.contributor.alternativeNameKim, Eung Kweon-
dc.contributor.alternativeNameLee, Hyung Keun-
dc.contributor.affiliatedAuthorKim, Eung Kweon-
dc.contributor.affiliatedAuthorLee, Hyung Keun-
dc.citation.volume55-
dc.citation.number5-
dc.citation.startPage646-
dc.citation.endPage655-
dc.identifier.bibliographicCitationJOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, Vol.55(5) : 646-655, 2014-
dc.identifier.rimsid56010-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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