Cited 10 times in
Receptor for Advanced Glycation End Products (RAGE) and Its Ligands: Focus on Spinal Cord Injury
DC Field | Value | Language |
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dc.contributor.author | 박경아 | - |
dc.contributor.author | 송주현 | - |
dc.contributor.author | 이원택 | - |
dc.contributor.author | 이종은 | - |
dc.date.accessioned | 2015-01-06T17:02:31Z | - |
dc.date.available | 2015-01-06T17:02:31Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1661-6596 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99248 | - |
dc.description.abstract | Spinal cord injury (SCI) results in neuronal and glial death and the loss of axons at the injury site. Inflammation after SCI leads to the inhibition of tissue regeneration and reduced neuronal survival. In addition, the loss of axons after SCI results in functional loss below the site of injury accompanied by neuronal cell body’s damage. Consequently, reducing inflammation and promoting axonal regeneration after SCI is a worthy therapeutic goal. The receptor for advanced glycation end products (RAGE) is a transmembrane protein and receptor of the immunoglobulin superfamily. RAGE is implicated in inflammation and neurodegeneration. Several recent studies demonstrated an association between RAGE and central nervous system disorders through various mechanisms. However, the relationship between RAGE and SCI has not been shown. It is imperative to elucidate the association between RAGE and SCI, considering that RAGE relates to inflammation and axonal degeneration following SCI. Hence, the present review highlights recent research regarding RAGE as a compelling target for the treatment of SCI. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 13172~13191 | - |
dc.language | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.publisher | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Inflammation/metabolism | - |
dc.subject.MESH | Inflammation/pathology | - |
dc.subject.MESH | Ligands* | - |
dc.subject.MESH | Receptor for Advanced Glycation End Products | - |
dc.subject.MESH | Receptors, Immunologic/chemistry | - |
dc.subject.MESH | Receptors, Immunologic/metabolism* | - |
dc.subject.MESH | Schwann Cells/cytology | - |
dc.subject.MESH | Schwann Cells/metabolism | - |
dc.subject.MESH | Spinal Cord Injuries/metabolism | - |
dc.subject.MESH | Spinal Cord Injuries/pathology* | - |
dc.title | Receptor for Advanced Glycation End Products (RAGE) and Its Ligands: Focus on Spinal Cord Injury | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anatomy (해부학) | - |
dc.contributor.googleauthor | Juhyun Song | - |
dc.contributor.googleauthor | Won Taek Lee | - |
dc.contributor.googleauthor | Kyung Ah Park | - |
dc.contributor.googleauthor | Jong Eun Lee | - |
dc.identifier.doi | 10.3390/ijms150813172 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01424 | - |
dc.contributor.localId | A02063 | - |
dc.contributor.localId | A03007 | - |
dc.contributor.localId | A03146 | - |
dc.relation.journalcode | J01133 | - |
dc.identifier.eissn | 1422-0067 | - |
dc.identifier.pmid | 25068700 | - |
dc.contributor.alternativeName | Park, Kyung Ah | - |
dc.contributor.alternativeName | Song, Ju Hyun | - |
dc.contributor.alternativeName | Lee, Won Taek | - |
dc.contributor.alternativeName | Lee, Jong Eun | - |
dc.contributor.affiliatedAuthor | Park, Kyung Ah | - |
dc.contributor.affiliatedAuthor | Song, Ju Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Won Taek | - |
dc.contributor.affiliatedAuthor | Lee, Jong Eun | - |
dc.citation.volume | 15 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 13172 | - |
dc.citation.endPage | 13191 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.15(8) : 13172-13191, 2014 | - |
dc.identifier.rimsid | 55963 | - |
dc.type.rims | ART | - |
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