Cited 18 times in
Evaluation of thyroid eye disease: Quality-of-life questionnaire (TED-QOL) in Korean patients
DC Field | Value | Language |
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dc.contributor.author | 손병재 | - |
dc.contributor.author | 윤진숙 | - |
dc.contributor.author | 이상열 | - |
dc.date.accessioned | 2015-01-06T17:01:41Z | - |
dc.date.available | 2015-01-06T17:01:41Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0008-4182 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99228 | - |
dc.description.abstract | OBJECTIVE:To assess impaired quality of life (QOL) of Korean patients with thyroid eye disease (TED) using the TED-QOL questionnaire, to evaluate the adaptability of the questionnaire, and to assess the correlation between TED-QOL and scales of disease severity. DESIGN:Prospective, cross-sectional study. PARTICIPANTS:Total of 90 consecutive adult patients with TED and Graves' disease were included in this study. METHODS:TED-QOL was translated into Korean and administered to the patients. The results were compared with clinical severity scores (clinical activity score, VISA (vision loss (optic neuropathy); inflammation; strabismus/motility; appearance/exposure) classification, modified NOSPECS (no signs or symptoms; only signs; soft tissue; proptosis; extraocular muscle; cornea; sight loss) score, Gorman diplopia scale, and European Group of Graves' Orbitopathy Classification). RESULTS:Clinical scores indicating inflammation and strabismus in patients with TED were positively correlated with overall and visual function-related QOL (Spearman coefficient 0.21-0.38, p < 0.05). Clinical scores associated with appearance were positively correlated with appearance-related QOL (Spearman coefficient 0.26-0.27, p < 0.05). In multivariate analysis, age, soft-tissue inflammation, motility disorder of modified NOSPECS, and motility disorder of VISA classification had positive correlation with overall and function-related QOL. Sex, soft-tissue inflammation, proptosis of modified NOSPECS, and appearance of VISA classification had correlation with appearance-related QOL. In addition, validity of TED-QOL was proved sufficient based on the outcomes of patient interviews and correlation between the subscales of TED-QOL. CONCLUSIONS:TED-QOL showed significant correlations with various objective clinical parameters of TED. TED-QOL was a simple and useful tool for rapid evaluation of QOL in daily outpatient clinics, which could be readily translated into different languages to be widely applicable to various populations. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 167~173 | - |
dc.relation.isPartOf | CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Asian Continental Ancestry Group/ethnology | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Graves Ophthalmopathy/ethnology | - |
dc.subject.MESH | Graves Ophthalmopathy/psychology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Quality of Life/psychology* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Surveys and Questionnaires* | - |
dc.subject.MESH | Visual Acuity/physiology | - |
dc.subject.MESH | Young Adult | - |
dc.title | Evaluation of thyroid eye disease: Quality-of-life questionnaire (TED-QOL) in Korean patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Byeong Jae Son | - |
dc.contributor.googleauthor | Sang Yeul Lee | - |
dc.contributor.googleauthor | Jin Sook Yoon | - |
dc.identifier.doi | 10.1016/j.jcjo.2013.12.007 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01970 | - |
dc.contributor.localId | A02611 | - |
dc.contributor.localId | A02819 | - |
dc.relation.journalcode | J00431 | - |
dc.identifier.eissn | 1715-3360 | - |
dc.identifier.pmid | 24767223 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0008418214000052 | - |
dc.contributor.alternativeName | Son, Byeong Jae | - |
dc.contributor.alternativeName | Yoon, Jin Sook | - |
dc.contributor.alternativeName | Lee, Sang Yeul | - |
dc.contributor.affiliatedAuthor | Son, Byeong Jae | - |
dc.contributor.affiliatedAuthor | Yoon, Jin Sook | - |
dc.contributor.affiliatedAuthor | Lee, Sang Yeul | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 49 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 167 | - |
dc.citation.endPage | 173 | - |
dc.identifier.bibliographicCitation | CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE, Vol.49(2) : 167-173, 2014 | - |
dc.identifier.rimsid | 55948 | - |
dc.type.rims | ART | - |
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