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Clinical Outcome of Successful Percutaneous Coronary Intervention for Chronic Total Occlusion: Results From the Multicenter Korean Chronic Total Occlusion (K-CTO) Registry.

 Byeong-Keuk Kim  ;  Sanghoon Shin  ;  Dong-Ho Shin  ;  Myeong-Ki Hong  ;  Hyeon-Cheol Gwon  ;  Hyo-Soo Kim  ;  Cheol Woong Yu  ;  Hun Sik Park  ;  In-Ho Chae  ;  Seung-Woon Rha  ;  Seung-Hwan Lee  ;  Moo-Hyun Kim  ;  Seung-Ho Hur  ;  Yangsoo Jang 
 JOURNAL OF INVASIVE CARDIOLOGY, Vol.26(6) : 255-259, 2014 
Journal Title
Issue Date
Aged ; Coronary Occlusion/epidemiology* ; Coronary Occlusion/therapy* ; Drug-Eluting Stents* ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Percutaneous Coronary Intervention/instrumentation ; Percutaneous Coronary Intervention/methods* ; Registries ; Republic of Korea/epidemiology ; Retrospective Studies ; Treatment Outcome
coronary occlusion ; drug-eluting stents ; clinical outcomes
OBJECTIVES: To investigate the impact of the success or failure of chronic total occlusion (CTO) interventions on the clinical outcomes in the current drug-eluting stent (DES) era. BACKGROUND: The impact of the successful CTO intervention on long-term clinical outcomes still remains unclear. METHODS: Between 2007 and 2009, a total of 2568 patients with CTO were followed in a multicenter Korean CTO registry. Of these, successful recanalization with DESs occurred in 2045 patients (successful CTO group), whereas failure occurred in 523 patients (failed CTO group). RESULTS: The occurrence of the composite of cardiac death and myocardial infarction (MI) was compared between the successful CTO and failed CTO groups. During follow-up (median duration, 729 days), the occurrence of cardiac death or MI was significantly lower in the successful CTO group than in the failed CTO group (1.7% vs 3.3%; hazard ratio, 0.50; 95% confidence interval, 0.28-0.91; P=.02) and the cumulative occurrence in the successful CTO group was also significantly lower than in the failed CTO group (1.7% vs 3.0%; P=.03) by the Kaplan-Meier method. The successful CTO group had a significantly lower need for bypass surgery than the failed CTO group (0.2% vs 2.5%; P<.001). In multivariate analysis, procedural success of CTO (odds ratio, 0.51; 95% CI, 0.29-0.92) was significantly predictive of the occurrence of cardiac death or MI, together with age and left ventricular ejection fraction <40%. CONCLUSION: This registry study demonstrated that successful CTO intervention with DESs compared to failed CTO intervention was associated with lower event rates during follow-up.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Byeong Keuk(김병극) ORCID logo https://orcid.org/0000-0003-2493-066X
Shin, Dong Ho(신동호) ORCID logo https://orcid.org/0000-0002-7874-5542
Shin, Sang Hoon(신상훈)
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Hong, Myeong Ki(홍명기) ORCID logo https://orcid.org/0000-0002-2090-2031
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