Cited 13 times in
Hierarchical cluster analysis of progression patterns in open-angle glaucoma patients with medical treatment
DC Field | Value | Language |
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dc.contributor.author | 김찬윤 | - |
dc.contributor.author | 배형원 | - |
dc.contributor.author | 성공제 | - |
dc.contributor.author | 이나은 | - |
dc.contributor.author | 홍사민 | - |
dc.date.accessioned | 2015-01-06T16:50:51Z | - |
dc.date.available | 2015-01-06T16:50:51Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0146-0404 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98884 | - |
dc.description.abstract | PURPOSE: To classify medically treated open-angle glaucoma (OAG) by the pattern of progression using hierarchical cluster analysis, and to determine OAG progression characteristics by comparing clusters. METHODS: Ninety-five eyes of 95 OAG patients who received medical treatment, and who had undergone visual field (VF) testing at least once per year for 5 or more years. OAG was classified into subgroups using hierarchical cluster analysis based on the following five variables: baseline mean deviation (MD), baseline visual field index (VFI), MD slope, VFI slope, and Glaucoma Progression Analysis (GPA) printout. After that, other parameters were compared between clusters. RESULTS: Two clusters were made after a hierarchical cluster analysis. Cluster 1 showed -4.06 ± 2.43 dB baseline MD, 92.58% ± 6.27% baseline VFI, -0.28 ± 0.38 dB per year MD slope, -0.52% ± 0.81% per year VFI slope, and all "no progression" cases in GPA printout, whereas cluster 2 showed -8.68 ± 3.81 baseline MD, 77.54 ± 12.98 baseline VFI, -0.72 ± 0.55 MD slope, -2.22 ± 1.89 VFI slope, and seven "possible" and four "likely" progression cases in GPA printout. There were no significant differences in age, sex, mean IOP, central corneal thickness, and axial length between clusters. However, cluster 2 included more high-tension glaucoma patients and used a greater number of antiglaucoma eye drops significantly compared with cluster 1. CONCLUSIONS: Hierarchical cluster analysis of progression patterns divided OAG into slow and fast progression groups, evidenced by assessing the parameters of glaucomatous progression in VF testing. In the fast progression group, the prevalence of high-tension glaucoma was greater and the number of antiglaucoma medications administered was increased versus the slow progression group. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 3231~3236 | - |
dc.relation.isPartOf | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Antihypertensive Agents/administration & dosage* | - |
dc.subject.MESH | Cluster Analysis | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Glaucoma, Open-Angle/diagnosis* | - |
dc.subject.MESH | Glaucoma, Open-Angle/drug therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraocular Pressure* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Ophthalmic Solutions | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Visual Field Tests | - |
dc.subject.MESH | Visual Fields* | - |
dc.title | Hierarchical cluster analysis of progression patterns in open-angle glaucoma patients with medical treatment | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Hyoung Won Bae | - |
dc.contributor.googleauthor | Seungsoo Rho | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Naeun Lee | - |
dc.contributor.googleauthor | Samin Hong | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.contributor.googleauthor | Kyung Rim Sung | - |
dc.contributor.googleauthor | Chan Yun Kim | - |
dc.identifier.doi | 10.1167/iovs.13-13856 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01035 | - |
dc.contributor.localId | A01814 | - |
dc.contributor.localId | A01946 | - |
dc.contributor.localId | A02704 | - |
dc.contributor.localId | A04395 | - |
dc.relation.journalcode | J01187 | - |
dc.identifier.eissn | 1552-5783 | - |
dc.identifier.pmid | 24781944 | - |
dc.identifier.url | http://www.iovs.org/content/55/5/3231.long | - |
dc.subject.keyword | hierarchical cluster analysis | - |
dc.subject.keyword | open-angle glaucoma | - |
dc.subject.keyword | progression | - |
dc.contributor.alternativeName | Kim, Chan Yun | - |
dc.contributor.alternativeName | Bae, Hyoung Won | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.alternativeName | Lee, Na Eun | - |
dc.contributor.alternativeName | Hong, Sa Min | - |
dc.contributor.affiliatedAuthor | Kim, Chan Yun | - |
dc.contributor.affiliatedAuthor | Bae, Hyoung Won | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Lee, Na Eun | - |
dc.contributor.affiliatedAuthor | Hong, Sa Min | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 55 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 3231 | - |
dc.citation.endPage | 3236 | - |
dc.identifier.bibliographicCitation | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol.55(5) : 3231-3236, 2014 | - |
dc.identifier.rimsid | 53759 | - |
dc.type.rims | ART | - |
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