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Epithelial Wound Healing after Cataract Surgery Comparing Two Different Topical Fluoroquinolones

DC Field Value Language
dc.contributor.author김세경-
dc.contributor.author김응권-
dc.contributor.author김태임-
dc.contributor.author정우석-
dc.contributor.author한경은-
dc.date.accessioned2015-01-06T16:37:50Z-
dc.date.available2015-01-06T16:37:50Z-
dc.date.issued2014-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98463-
dc.description.abstractPURPOSE: To compare the epithelial wound healing response of two preservative-free fluoroquinolones, moxifloxacin and levofloxacin, in patients who underwent cataract surgery. MATERIALS AND METHODS: In this prospective, evaluator-masked, randomized clinical trial, 59 eyes of 50 patients who underwent cataract surgery were enrolled. Patients were randomized to receive moxifloxacin 0.5% (n=32 eyes) or levofloxacin 0.5% (n=27 eyes). All patients instilled moxifloxacin or levofloxain four times daily for 1 week prior to surgery and 2 weeks after surgery. The epithelial wound healing status in the corneal incision site was scanned with a raster scan mode of fourier-domain optical coherence tomography (FD-OCT). The number of eyes showing epithelial defect images and average number of corneal epithelial defect cuts per eye were compared between groups. All patients were evaluated on postoperative days 1, 2, 3, and 10. RESULTS: On postoperative days 1, 2, and 3, the number of eyes showing epithelial defects in FD-OCT was not statistically different (all p>0.05). The average number of corneal epithelial defect cuts was also not statistically different between the two groups (all p>0.05). No eyes showed epithelial defects on postoperative day 10 in either group. CONCLUSION: There were no differences on epithelial wound healing comparing these two different fluoroquinolones at the incision site of cataract surgery.-
dc.description.statementOfResponsibilityopen-
dc.format.extent197~202-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAza Compounds/therapeutic use-
dc.subject.MESHCataract Extraction-
dc.subject.MESHCornea/drug effects-
dc.subject.MESHCornea/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHFluoroquinolones/therapeutic use*-
dc.subject.MESHHumans-
dc.subject.MESHLevofloxacin/therapeutic use-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHQuinolines/therapeutic use-
dc.subject.MESHTomography, Optical Coherence-
dc.subject.MESHWound Healing/drug effects*-
dc.titleEpithelial Wound Healing after Cataract Surgery Comparing Two Different Topical Fluoroquinolones-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorKyung Eun Han-
dc.contributor.googleauthorWoo Suk Chung-
dc.contributor.googleauthorTae-im Kim-
dc.contributor.googleauthorSekyung Kim-
dc.contributor.googleauthorTerry Kim-
dc.contributor.googleauthorEung Kweon Kim-
dc.identifier.doi10.3349/ymj.2014.55.1.197-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04265-
dc.contributor.localIdA00600-
dc.contributor.localIdA00831-
dc.contributor.localIdA01080-
dc.contributor.localIdA03665-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid24339307-
dc.subject.keywordLevofloxacin-
dc.subject.keywordcataract surgery-
dc.subject.keywordepithelial wound healing-
dc.subject.keywordmoxifloxacin-
dc.contributor.alternativeNameKim, Se Kyung-
dc.contributor.alternativeNameKim, Eung Kweon-
dc.contributor.alternativeNameKim, Tae Im-
dc.contributor.alternativeNameChung, Woo Suk-
dc.contributor.alternativeNameHan, Kyung Eun-
dc.contributor.affiliatedAuthorHan, Kyung Eun-
dc.contributor.affiliatedAuthorKim, Se Kyung-
dc.contributor.affiliatedAuthorKim, Eung Kweon-
dc.contributor.affiliatedAuthorKim, Tae Im-
dc.contributor.affiliatedAuthorChung, Woo Suk-
dc.citation.volume55-
dc.citation.number1-
dc.citation.startPage197-
dc.citation.endPage202-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.55(1) : 197-202, 2014-
dc.identifier.rimsid57607-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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