Cited 64 times in
Osteoconductivity and biodegradation of synthetic bone substitutes with different tricalcium phosphate contents in rabbits
DC Field | Value | Language |
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dc.contributor.author | 최성호 | - |
dc.contributor.author | 김창성 | - |
dc.contributor.author | 어운희 | - |
dc.contributor.author | 이중석 | - |
dc.contributor.author | 정의원 | - |
dc.date.accessioned | 2015-01-06T16:35:38Z | - |
dc.date.available | 2015-01-06T16:35:38Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1552-4973 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98396 | - |
dc.description.abstract | Various synthetic bone substitutes have been developed to reconstruct the bony defects that clinicians often encounter during surgical procedures. Among various synthetic bone substitutes, calcium phosphate (Ca-P) ceramics have been investigated because their composition and structure are similar to those of human bone. We evaluated the bone healing and biodegradation patterns of three types of Ca-P ceramic particle with various hydroxyapatite (HA)/β-tricalcium phosphate (β-TCP) weight ratio: pure β-TCP, biphasic Ca-P (BCP) with a HA/β-TCP weight ratio of 60/40 (BCP 60/40), and BCP with an HA/β-TCP weight ratio of 20/80 (BCP 20/80). Four 8-mm-diameter defects were created in ten rabbits. Three of the defects in each rabbit were separately and randomly filled with one of the three experimental Ca-P ceramic particles, and the fourth was filled with blood clots (control). The specimens were harvested at 2 and 8 weeks post-surgery. The histologic and histometric findings revealed that the augmented space and new bone formation were significantly better for all three Ca-P ceramics than for the control group at both 2 and 8 weeks (p < 0.05). Compared to the pure β-TCP, the two BCP groups were found to provide a larger amount of newly formed bone and bone density at the 2- and 8-week post-operative periods (p < 0.05). Throughout the observation period, BCP 60/40 and BCP 20/80 exhibited a similar bone healing and biodegradation patterns with regard to both individual particles and the total augmented area in vivo. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 80~88 | - |
dc.relation.isPartOf | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Absorbable Implants | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Bone Regeneration | - |
dc.subject.MESH | Bone Substitutes/chemistry* | - |
dc.subject.MESH | Bone Substitutes/metabolism | - |
dc.subject.MESH | Calcium Phosphates/chemistry* | - |
dc.subject.MESH | Calcium Phosphates/metabolism | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Materials Testing | - |
dc.subject.MESH | Microscopy, Electron, Scanning | - |
dc.subject.MESH | Osseointegration | - |
dc.subject.MESH | Rabbits | - |
dc.subject.MESH | Skull/anatomy & histology | - |
dc.subject.MESH | Skull/physiology | - |
dc.subject.MESH | Skull/surgery | - |
dc.title | Osteoconductivity and biodegradation of synthetic bone substitutes with different tricalcium phosphate contents in rabbits | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Dental Engineering (치과생체재료공학) | - |
dc.contributor.googleauthor | Cheryl Yang | - |
dc.contributor.googleauthor | Otgonbayar Unursaikhan | - |
dc.contributor.googleauthor | Jung-Seok Lee | - |
dc.contributor.googleauthor | Ui-Won Jung | - |
dc.contributor.googleauthor | Chang-Sung Kim | - |
dc.contributor.googleauthor | Seong-Ho Choi | - |
dc.identifier.doi | 10.1002/jbm.b.32984 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01041 | - |
dc.contributor.localId | A02333 | - |
dc.contributor.localId | A03692 | - |
dc.contributor.localId | A03185 | - |
dc.contributor.localId | A04081 | - |
dc.relation.journalcode | J01267 | - |
dc.identifier.eissn | 1552-4981 | - |
dc.identifier.pmid | 23852942 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.32984/abstract | - |
dc.subject.keyword | beta tricalcium phosphate | - |
dc.subject.keyword | biodegradation | - |
dc.subject.keyword | bone regeneration | - |
dc.subject.keyword | hydroxyapatite | - |
dc.subject.keyword | synthetic bone graft | - |
dc.contributor.alternativeName | Choi, Seong Ho | - |
dc.contributor.alternativeName | Kim, Chang Sung | - |
dc.contributor.alternativeName | Unursaikhan, Otgonbayar | - |
dc.contributor.alternativeName | Lee, Jung Seok | - |
dc.contributor.alternativeName | Jung, Ui Won | - |
dc.contributor.affiliatedAuthor | Kim, Chang Sung | - |
dc.contributor.affiliatedAuthor | Unursaikhan, Otgonbayar | - |
dc.contributor.affiliatedAuthor | Jung, Ui Won | - |
dc.contributor.affiliatedAuthor | Lee, Jung Seok | - |
dc.contributor.affiliatedAuthor | Choi, Seong Ho | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 102B | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 80 | - |
dc.citation.endPage | 88 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol.102B(1) : 80-88, 2014 | - |
dc.identifier.rimsid | 56574 | - |
dc.type.rims | ART | - |
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