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Cited 29 times in

Efficacy of IP-10 as a biomarker for monitoring tuberculosis teratment

DC Field Value Language
dc.contributor.author김세규-
dc.contributor.author김송이-
dc.contributor.author김영삼-
dc.contributor.author김은영-
dc.contributor.author박무석-
dc.contributor.author장준-
dc.contributor.author정경수-
dc.contributor.author정지예-
dc.contributor.author조상래-
dc.contributor.author홍지영-
dc.contributor.author강영애-
dc.date.accessioned2015-01-06T16:35:27Z-
dc.date.available2015-01-06T16:35:27Z-
dc.date.issued2014-
dc.identifier.issn0163-4453-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98390-
dc.description.abstractOBJECTIVES: IP-10 has been proposed as a promising alternative marker for the diagnosis of tuberculosis (TB). METHODS: In this exploratory study, we assessed the levels of serum IP-10 and TB antigen-dependent IP-10 at the time of diagnosis and after completing treatment in 32 patients with active TB. RESULTS: Significant changes in concentration between the time of diagnosis and the completion of therapy were observed for serum IP-10 (P < 0.001; median: 140.4 and 105.7 pg/ml, respectively) and TB antigen-dependent IP-10 (P = 0.002; median: 20,000 and 13,720 pg/ml, respectively). The proportion of TB antigen-dependent IP-10 responders did not change significantly between baseline and the completion of therapy (P = 0.35), whereas the proportion of serum IP-10 responders was significantly different (P = 0.001). CONCLUSIONS: Serum IP-10 and TB antigen-dependent IP-10 responses to QFT-GIT antigens might be a useful biomarker for monitoring the efficacy of therapy in patients with active TB.-
dc.description.statementOfResponsibilityopen-
dc.format.extent252~258-
dc.relation.isPartOfJOURNAL OF INFECTION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHBiomarkers/blood*-
dc.subject.MESHChemokine CXCL10/blood*-
dc.subject.MESHDrug Monitoring-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInterferon-gamma/blood-
dc.subject.MESHLongitudinal Studies-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHTuberculosis/blood-
dc.subject.MESHTuberculosis/diagnosis*-
dc.subject.MESHTuberculosis/drug therapy*-
dc.subject.MESHTuberculosis/immunology-
dc.titleEfficacy of IP-10 as a biomarker for monitoring tuberculosis teratment-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJi Young Hong-
dc.contributor.googleauthorHye Jon Lee-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorKyung Soo Chung-
dc.contributor.googleauthorEun Young Kim-
dc.contributor.googleauthorJi Ye Jung-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorSe Kyu Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorSang-Nae Cho-
dc.contributor.googleauthorYoung Ae Kang-
dc.identifier.doi10.1016/j.jinf.2013.09.033-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00602-
dc.contributor.localIdA00626-
dc.contributor.localIdA00707-
dc.contributor.localIdA01457-
dc.contributor.localIdA03472-
dc.contributor.localIdA03570-
dc.contributor.localIdA03735-
dc.contributor.localIdA03824-
dc.contributor.localIdA00057-
dc.contributor.localIdA04441-
dc.contributor.localIdA00811-
dc.relation.journalcodeJ01452-
dc.identifier.eissn1532-2742-
dc.identifier.pmid24247066-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0163445313003368-
dc.subject.keywordIP-10-
dc.subject.keywordMonitoring-
dc.subject.keywordTuberculosis-
dc.contributor.alternativeNameKim, Se Kyu-
dc.contributor.alternativeNameKim, Song Yi-
dc.contributor.alternativeNameKim, Young Sam-
dc.contributor.alternativeNameKim, Eun Young-
dc.contributor.alternativeNamePark, Moo Suk-
dc.contributor.alternativeNameChang, Joon-
dc.contributor.alternativeNameJung, Kyung Soo-
dc.contributor.alternativeNameJung, Ji Ye-
dc.contributor.alternativeNameCho, Sang Nae-
dc.contributor.alternativeNameHong, Ji Young-
dc.contributor.alternativeNameKang, Young Ae-
dc.contributor.affiliatedAuthorKim, Se Kyu-
dc.contributor.affiliatedAuthorKim, Song Yi-
dc.contributor.affiliatedAuthorKim, Young Sam-
dc.contributor.affiliatedAuthorPark, Moo Suk-
dc.contributor.affiliatedAuthorChang, Joon-
dc.contributor.affiliatedAuthorJung, Kyung Soo-
dc.contributor.affiliatedAuthorJung, Ji Ye-
dc.contributor.affiliatedAuthorCho, Sang Nae-
dc.contributor.affiliatedAuthorKang, Young Ae-
dc.contributor.affiliatedAuthorHong , Ji Young-
dc.contributor.affiliatedAuthorKim, Eun Young-
dc.rights.accessRightsfree-
dc.citation.volume68-
dc.citation.number3-
dc.citation.startPage252-
dc.citation.endPage258-
dc.identifier.bibliographicCitationJOURNAL OF INFECTION, Vol.68(3) : 252-258, 2014-
dc.identifier.rimsid56570-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Microbiology (미생물학교실) > 1. Journal Papers

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