Current concept of abdominal sepsis: WSES position paper

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Authors: Massimo Sartelli ; Fausto Catena ; Salomone Di Saverio ; Luca Ansaloni ; Mark Malangoni ; Ernest E Moore ; Frederick A Moore ; Rao Ivatury ; Raul Coimbra ; Ari Leppaniemi ; Walter Biffl ; Yoram Kluger ; Gustavo P Fraga ; Carlos A Ordonez ; Sanjay Marwah ; Igor Gerych ; Jae Gil Lee ; Cristian Tranà ; Federico Coccolini ; Francesco Corradetti ; James Kirkby-Bott

Keywords: Septic Shock ; Severe Sepsis ; Tigecycline ; Open Abdomen ; Abdominal Sepsis

Abstract: Although sepsis is a systemic process, the pathophysiological cascade of events may vary from region to region.

Abdominal sepsis represents the host’s systemic inflammatory response to bacterial peritonitis.

It is associated with significant morbidity and mortality rates, and is the second most common cause of sepsis-related mortality in the intensive care unit.

The review focuses on sepsis in the specific setting of severe peritonitis.