115 210

Cited 9 times in

Periarticular Injection with Corticosteroid Has an Additional Pain Management Effect in Total Knee Arthroplasty

 Sae Kwang Kwon  ;  Ick Hwan Yang  ;  Sun Joon Bai  ;  Chang Dong Han 
 YONSEI MEDICAL JOURNAL, Vol.55(2) : 493-498, 2014 
Journal Title
Issue Date
Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/therapeutic use* ; Aged ; Aged, 80 and over ; Anesthetics, Local/therapeutic use ; Arthroplasty, Replacement, Knee* ; Double-Blind Method ; Female ; Humans ; Injections, Intra-Articular ; Middle Aged ; Morphine/therapeutic use ; Pain Management/methods* ; Pain, Postoperative/drug therapy* ; Patient Satisfaction ; Prospective Studies ; Treatment Outcome ; Triamcinolone Acetonide/administration & dosage ; Triamcinolone Acetonide/therapeutic use*
Corticosteroid ; pain ; periarticular injection ; total knee arthroplasty
PURPOSE: Although the analgesic effects of corticosteroids have been well documented, little information is available on periarticular injection (PI) containing corticosteroids for early postoperative pain management after total knee arthroplasty (TKA). We performed a prospective double-blind randomized trial to evaluate the efficacy and safety of an intraoperative corticosteroid PI in patients undergoing TKA. MATERIALS AND METHODS: Seventy-six consecutive female patients undergoing bilateral staged TKA were randomized to receive steroid or non-steroid PI, with 3 months separating the procedures. The steroid group received PI with a mixture containing triamcinolone acetonide (40 mg). The non-steroid group received the same injection mixture without corticosteroid. During the postoperative period, nighttime pain, functional recovery [straight leg raising (SLR) ability and maximal flexion], patient satisfaction, and complications were recorded. Short-term postoperative clinical scores and patient satisfaction were evaluated at 6 months. RESULTS: The pain level was significantly lower in the PI steroid than the non-steroid group on the night of the operation (VAS, 1.2 vs. 2.3; p=0.021). Rebound pain was observed in both groups at POD1 (VAS, 3.2 vs. 3.8; p=0.248), but pain remained at a low level thereafter. No significant differences were seen in maximal flexion, frequency of acute rescuer, clinical scores, and patient satisfaction. The steroid group was able to perform SLR earlier than the non-steroid group (p=0.013). The incidence of complications was similar between the groups. CONCLUSION: PI containing a corticosteroid provided an additional pain-relieving effect on the night of the operation. In addition, corticosteroid PI did not increase the perioperative complications of TKA.
Files in This Item:
T201400526.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Bai, Sun Joon(배선준) ORCID logo https://orcid.org/0000-0001-5027-3232
Yang, Ick Hwan(양익환)
Han, Chang Dong(한창동)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.