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Pretransplant mortality predictors in living and deceased donor liver transplantation

 Youn Yi Jo  ;  Yong Seon Choi  ;  Dong Jin Joo  ;  Young-Chul Yoo  ;  Seung Gyun Nam  ;  Shin Ok Koh 
 Journal of the Chinese Medical Association, Vol.77(1) : 16-20, 2014 
Journal Title
 Journal of the Chinese Medical Association 
Issue Date
BACKGROUND: Although there were some reports predicting postoperative morbidity and mortality in patients undergoing liver transplantation, most of them studied deceased-donor liver transplantation (DDLT). In this context, we performed this study to predict early mortality after liver transplantation from preoperative variables in both living-donor liver transplantation (LDLT) and DDLT. METHODS: We retrospectively reviewed the medical charts of 159 patients undergoing liver transplantation (LDLT, n = 103; DDLT, n = 56). Then, we identified the factors that independently predicted 30-day mortality using multivariable logistic regression models. RESULTS: The 30-day mortality and 1-year mortality for DDLT versus LDLT were 30% versus 6% and 39% versus 11%, respectively. In multivariate logistic regression analysis, pretransplant hepatic encephalopathy (odds ratio, 5.594; 95% confidence interval, 1.110-28.194; p = 0.037) in patients with DDLT and serum creatinine (odds ratio, 4.883; 95% confidence interval, 1.296-18.399; p = 0.019) in patients with LDLT were the independent risk factors for a composite of 30-day mortality. CONCLUSION: In conclusion, hepatic encephalopathy in DDLT and serum creatinine level in LDLT were the significant pretransplant variables that were related with early death after LT.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Shin Ok(고신옥)
Yoo, Young Chul(유영철) ORCID logo https://orcid.org/0000-0002-6334-7541
Joo, Dong Jin(주동진) ORCID logo https://orcid.org/0000-0001-8405-1531
Choi, Yong Seon(최용선) ORCID logo https://orcid.org/0000-0002-5348-864X
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