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Evaluation of elevated urinary enolase I levels in patients with endometriosis.

DC Field Value Language
dc.contributor.author김혜연-
dc.contributor.author박주현-
dc.contributor.author서석교-
dc.contributor.author윤보현-
dc.contributor.author이병석-
dc.contributor.author임수연-
dc.contributor.author전승주-
dc.contributor.author정연수-
dc.contributor.author조시현-
dc.contributor.author최영식-
dc.date.accessioned2015-01-06T16:26:01Z-
dc.date.available2015-01-06T16:26:01Z-
dc.date.issued2014-
dc.identifier.issn1354-750X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98096-
dc.description.abstractOBJECTIVE: The aim of this study is to validate and investigate the clinical value of urinary enolase I in patients with endometriosis. METHODS: Urine samples of 39 patients with histologically confirmed endometriosis and 20 patients without endometriosis were collected. Western blot analysis and enzyme-linked immunosorbent assay were used to detect the increase of enolase I in patients' urine. RESULTS: Urinary enolase I expression corrected for creatinine ratio (non neuronal enolase (NNE)-Cr) was significantly greater in patients with endometriosis (p = 0.026). When the diagnostic performance of NNE-Cr was evaluated with serum CA-125 combination, the area under the curve was 0.821 (95% confidence interval 0.713-0.928) with sensitivity and specificity of 76.9% and 85.0%, respectively. CONCLUSION: Elevated urinary enolase I, in conjunction with serum CA-125, may be used as a potential biomarker for endometriosis.-
dc.description.statementOfResponsibilityopen-
dc.format.extent16~21-
dc.relation.isPartOfBIOMARKERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBiomarkers/urine-
dc.subject.MESHBiomarkers, Tumor/urine*-
dc.subject.MESHCA-125 Antigen/blood-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHCreatinine/urine-
dc.subject.MESHDNA-Binding Proteins/urine*-
dc.subject.MESHEndometriosis/diagnosis-
dc.subject.MESHEndometriosis/enzymology-
dc.subject.MESHEndometriosis/urine*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHPhosphopyruvate Hydratase/urine*-
dc.subject.MESHROC Curve-
dc.subject.MESHTumor Suppressor Proteins/urine*-
dc.titleEvaluation of elevated urinary enolase I levels in patients with endometriosis.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Obstetrics & Gynecology (산부인과학)-
dc.contributor.googleauthorBo Hyon Yun-
dc.contributor.googleauthorYou Sun Lee-
dc.contributor.googleauthorSeung Joo Chon-
dc.contributor.googleauthorYeon Soo Jung-
dc.contributor.googleauthorSu Youn Yim-
dc.contributor.googleauthorHye Yeon Kim-
dc.contributor.googleauthorJoo Hyun Park-
dc.contributor.googleauthorSeok Kyo Seo-
dc.contributor.googleauthorSiHyun Cho-
dc.contributor.googleauthorYoung Sik Choi-
dc.contributor.googleauthorByung Seok Lee-
dc.identifier.doi10.3109/1354750X.2013.863973-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04820-
dc.contributor.localIdA01174-
dc.contributor.localIdA01668-
dc.contributor.localIdA01888-
dc.contributor.localIdA02555-
dc.contributor.localIdA02795-
dc.contributor.localIdA03527-
dc.contributor.localIdA03846-
dc.contributor.localIdA04114-
dc.relation.journalcodeJ00311-
dc.identifier.eissn1366-5804-
dc.identifier.pmid24283984-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.3109/1354750X.2013.863973-
dc.subject.keywordBiomarker-
dc.subject.keywordendometriosis-
dc.subject.keywordenolase I-
dc.subject.keywordurine-
dc.contributor.alternativeNameKim, Hye Yeon-
dc.contributor.alternativeNamePark, Joo Hyun-
dc.contributor.alternativeNameSeo, Seok Kyo-
dc.contributor.alternativeNameYun, Bo Hyon-
dc.contributor.alternativeNameLee, Byung Seok-
dc.contributor.alternativeNameYim, Su Youn-
dc.contributor.alternativeNameChon, Seung Joo-
dc.contributor.alternativeNameJeong, Yon Soo-
dc.contributor.alternativeNameCho, Si Hyun-
dc.contributor.alternativeNameChoi, Young Sik-
dc.contributor.affiliatedAuthorYim, Su Youn-
dc.contributor.affiliatedAuthorKim, Hye Yeon-
dc.contributor.affiliatedAuthorPark, Joo Hyun-
dc.contributor.affiliatedAuthorSeo, Seok Kyo-
dc.contributor.affiliatedAuthorYun, Bo Hyon-
dc.contributor.affiliatedAuthorLee, Byung Seok-
dc.contributor.affiliatedAuthorChon, Seung Joo-
dc.contributor.affiliatedAuthorCho, Si Hyun-
dc.contributor.affiliatedAuthorChoi, Young Sik-
dc.rights.accessRightsfree-
dc.citation.volume19-
dc.citation.number1-
dc.citation.startPage16-
dc.citation.endPage21-
dc.identifier.bibliographicCitationBIOMARKERS, Vol.19(1) : 16-21, 2014-
dc.identifier.rimsid54886-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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