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Autobiographical memory and its association with neuropsychological function in bipolar disorder

 Woo Jung Kim  ;  Ra Yeon Ha  ;  Ja Yeun Sun  ;  Vin Ryu  ;  Su Jin Lee  ;  Kyooseob Ha  ;  Hyun-Sang Cho 
 COMPREHENSIVE PSYCHIATRY, Vol.55(2) : 290-297, 2014 
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Adult ; Bipolar Disorder/physiopathology* ; Executive Function/physiology* ; Female ; Humans ; Intelligence/physiology ; Male ; Memory, Episodic* ; Middle Aged ; Neuropsychological Tests* ; Young Adult
OBJECTIVE: The aim of this study was to investigate the overgeneralization of autobiographical memory (AM) in bipolar disorder (BD) and assess its association with multiple cognitive domains. METHOD: Twenty-eight clinically stable bipolar I patients and an equal number of age- and gender-matched healthy controls (HC) were included. All participants were examined using the autobiographical memory test (AMT) and the neuropsychological battery including the general intelligence, attention, verbal memory, verbal fluency, visual memory, and executive functions domain. Demographic, clinical, and test variables were compared between BD and HC groups. Correlation analyses of AMT scores with cognitive functions were performed within each group, controlling for demographic and clinical variables. RESULTS: Total and negative scores of AMT were significantly lower in BD patients compared to HC individuals. AMT scores were significantly correlated with WAIS similarities, WCST perseverative errors, and WCST categories completed in BD, whereas AMT scores were correlated with verbal memory and verbal fluency in HC. CONCLUSION: Our findings suggest that overgeneral AM is a characteristic of BD and is related to executive function. Future studies should investigate the benefit of additional treatment focusing on overgeneral AM in BD.
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1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Ryu, Vin(유빈)
Cho, Hyun Sang(조현상) ORCID logo https://orcid.org/0000-0003-1019-9941
Ha, Ra Yeon(하라연)
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