Over the past several decades, great strides have been made in diagnosis, treatment, and survival of childhood cancer. In the 1960s the probability of survival for a child with cancer was less than 25%, whereas today it may exceed 70%. This dramatic change has occurred through significant and steady progress in our understanding of tumor biology, creation of specialized multidisciplinary care teams, incremental improvements in therapy. Also, recent progress in the understanding of psychological and social factors related to cancer is important because cancer is the most common fatal disease of childhood and adolescence. Research interest in children and adolescents who have survived cancer also has increased over the past several years. Attention has focused on the long-term socal outcomes of these children and adolescents. As health-related research on children shift from seeking information about children to seeking information directly form them, researchers recognize the need for developmentally appropriate methods such as drawing, playing, and music to help children communicate their experiences.