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Non-Hodgkin's lymphoma of the sphenoid sinus presenting as isolated oculomotro never palsy

Authors
 Young Mok Park  ;  Jun Hyung Cho  ;  Jung Yong Ahn  ;  Ji Soon Huh  ;  Jae Yong Cho 
Citation
 WORLD JOURNAL OF SURGICAL ONCOLOGY, Vol.5 : 86, 2007 
Journal Title
 WORLD JOURNAL OF SURGICAL ONCOLOGY 
Issue Date
2007
Abstract
BACKGROUND: Solitary involvement of the sphenoid sinus has rarely been reported in non-Hodgkin's lymphoma. Isolated oculomotor nerve palsy is uncommon as an initial presentation of malignant tumors of the sphenoid sinus. CASE PRESENTATION: A 53-year-old woman presented with a three-month history of headache and diplopia. Neurological examination revealed complete left oculomotor nerve palsy. Magnetic Resonance Imaging (MRI) demonstrated a homogenous soft-tissue lesion occupying the left sphenoid sinus and invading the left cavernous sinus. The patient underwent transsphenoidal biopsy and the lesion was histologically diagnosed as non-Hodgkin's lymphoma, diffuse large B-cell type. Tumor cells were positive for CD20 and negative for CD3. Following six cycles of chemotherapy, the left oculomotor nerve palsy that had been previously observed was completely resolved. There was no enhancing lesion noted on follow-up MRI. CONCLUSION: It is important to recognize that non-Hodgkin's lymphoma of the sphenoid sinus can present with isolated oculomotor nerve palsy, although it is extremely rare. The cranial nerve deficits can resolve dramatically after chemotherapy.
Files in This Item:
T200701310.pdf Download
DOI
10.1186/1477-7819-5-86
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Ahn, Jung Yong(안정용)
Cho, Jae Yong(조재용) ORCID logo https://orcid.org/0000-0002-0926-1819
Cho, Jun Hyung(조준형)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97453
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