Cited 11 times in
Outcomes of three patients with intracranially invasive Sino-orbital aspergillosis
DC Field | Value | Language |
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dc.contributor.author | 윤진숙 | - |
dc.contributor.author | 이상열 | - |
dc.contributor.author | 조남훈 | - |
dc.date.accessioned | 2014-12-21T17:15:06Z | - |
dc.date.available | 2014-12-21T17:15:06Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0740-9303 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/97234 | - |
dc.description.abstract | PURPOSE: Although rare, invasive aspergillosis with intracranial spread usually is fatal and necessitates prompt diagnosis and treatment. We describe the prognoses for survival and vision in 3 consecutive patients with vision-threatening invasive sino-orbital aspergillosis. METHODS: A case series of 3 patients, with review of treatments and outcomes. RESULTS: Three diabetic patients presented with significant eye pain and headache, followed by progressive ophthalmic symptoms including vision loss and limitation of ocular motility. Histologic examination showed numerous hyphae of Aspergillus fumigatus. Following early diagnosis and surgical debridement, 1 patient (case 1) showed vision improvement, from counting fingers to 20/20. The other 2 patients, who were initially treated with corticosteroids after presumptive diagnoses of nonspecific orbital inflammation, showed no recovery of vision from no light perception, and 1 (case 3) died of massive intracranial spread and side effects of antifungal agents caused by delayed diagnosis and long-term use of corticosteroids. CONCLUSIONS: Invasive sino-orbital aspergillosis with intracranial invasion often may resemble inflammatory conditions. Early diagnosis and surgical intervention are required to improve vision and survival. Repeated biopsies often are necessary to rule out fungal sinus infection before considering steroid use, especially in diabetic patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 400~406 | - |
dc.relation.isPartOf | OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Outcomes of three patients with intracranially invasive Sino-orbital aspergillosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Jin Sook Yoon | - |
dc.contributor.googleauthor | Hyung Kyu Park | - |
dc.contributor.googleauthor | Sang Yeul Lee | - |
dc.contributor.googleauthor | Nam Hoon Cho | - |
dc.identifier.doi | 10.1097/IOP.0b013e31814db448 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02611 | - |
dc.contributor.localId | A02819 | - |
dc.contributor.localId | A03812 | - |
dc.relation.journalcode | J02427 | - |
dc.identifier.eissn | 1537-2677 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00002341-200709000-00014&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Yoon, Jin Sook | - |
dc.contributor.alternativeName | Lee, Sang Yeul | - |
dc.contributor.alternativeName | Cho, Nam Hoon | - |
dc.contributor.affiliatedAuthor | Yoon, Jin Sook | - |
dc.contributor.affiliatedAuthor | Lee, Sang Yeul | - |
dc.contributor.affiliatedAuthor | Cho, Nam Hoon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 23 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 400 | - |
dc.citation.endPage | 406 | - |
dc.identifier.bibliographicCitation | OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, Vol.23(5) : 400-406, 2007 | - |
dc.identifier.rimsid | 57819 | - |
dc.type.rims | ART | - |
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