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Papillary thyroid carcinoma with thyroid-associated orbitopathy in a euthyroid state

DC Field Value Language
dc.contributor.author박정수-
dc.contributor.author윤진숙-
dc.contributor.author이상열-
dc.contributor.author남기현-
dc.date.accessioned2014-12-21T17:15:03Z-
dc.date.available2014-12-21T17:15:03Z-
dc.date.issued2007-
dc.identifier.issn0740-9303-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/97232-
dc.description.abstractPURPOSE: Thyroid cancers with concurrent thyroid-associated orbitopathy (TAO) are extremely rare. The present study reports 5 unusual cases of papillary thyroid microcarcinoma in patients presenting with TAO in an euthyroid state. METHODS: We retrospectively reviewed the records of 5 patients (4 female, 1 male) with no known history of thyroid disease, who initially presented with TAO and were subsequently found to have thyroid cancer. TAO was diagnosed by a combination of computed tomography and clinical symptoms and signs. All patients underwent routine serologic assessment of thyroid hormones and thyroid-related autoantibodies including thyrotropin-receptor antibodies, as well as imaging studies such as neck ultrasonography or thyroid scintiscan with I. RESULTS: Patients presented with asymmetric proptosis (cases 1-3), ocular motility restriction (cases 1-3), and eyelid retraction (cases 1-5). None of the patients showed clinical signs of hyperthyroidism, and all returned normal thyroid function test data. Thyroid nodules were detected by neck imaging; subsequent fine-needle aspiration biopsies were performed with the cytologic result of papillary carcinoma. In no cases did ophthalmic symptoms resolve following cancer treatment (e.g., thyroidectomy and radioactive iodine therapy). All patients were positive for thyroid-binding inhibiting immunoglobulin in low titers. CONCLUSIONS: Although coincident occurrence is rare, patients presenting with TAO should be carefully evaluated for the possible presence of papillary microcarcinoma, which can develop in a setting of systemic autoimmunity without inducing hyperthyroidism.-
dc.description.statementOfResponsibilityopen-
dc.format.extent187~191-
dc.relation.isPartOfOPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titlePapillary thyroid carcinoma with thyroid-associated orbitopathy in a euthyroid state-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorJin Sook Yoon-
dc.contributor.googleauthorHelen Lew-
dc.contributor.googleauthorSang Yeul Lee-
dc.contributor.googleauthorKi Hyun Nam-
dc.contributor.googleauthorJeong Soo Park-
dc.identifier.doi10.1097/IOP.0b013e31803e1755-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01646-
dc.contributor.localIdA02611-
dc.contributor.localIdA02819-
dc.contributor.localIdA01245-
dc.relation.journalcodeJ02427-
dc.identifier.eissn1537-2677-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00002341-200705000-00004&LSLINK=80&D=ovft-
dc.contributor.alternativeNamePark, Cheong Soo-
dc.contributor.alternativeNameYoon, Jin Sook-
dc.contributor.alternativeNameLee, Sang Yeul-
dc.contributor.alternativeNameNam, Kee Hyun-
dc.contributor.affiliatedAuthorPark, Cheong Soo-
dc.contributor.affiliatedAuthorYoon, Jin Sook-
dc.contributor.affiliatedAuthorLee, Sang Yeul-
dc.contributor.affiliatedAuthorNam, Kee Hyun-
dc.rights.accessRightsnot free-
dc.citation.volume23-
dc.citation.number3-
dc.citation.startPage187-
dc.citation.endPage191-
dc.identifier.bibliographicCitationOPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, Vol.23(3) : 187-191, 2007-
dc.identifier.rimsid57818-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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