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한국 소아 수모세포종의 다기관 치료 성적

Other Titles
 Outcome of Multicenter Study for Korean Children with Medulloblastoma 
 박현진  ;  남병호  ;  황태주  ;  최중언  ;  최은진  ;  조빈  ;  조병규  ;  정혜림  ;  정대철  ;  정낙균  ;  임호준  ;  임도훈  ;  이준아  ;  이영호  ;  이순용  ;  이건수  ;  유철주  ;  유은선  ;  유경하  ;  유건희  ;  왕규창  ;  안효섭  ;  안승도  ;  신형진  ;  성기웅  ;  서창옥  ;  서종진  ;  백희조  ;  박지경  ;  박준은  ;  박상규  ;  박병규  ;  박경덕  ;  문형남  ;  나영신  ;  김흥식  ;  김학기  ;  김태형  ;  김지윤  ;  김일한  ;  김승기  ;  김동석  ;  국훈  ;  구홍회  ;  강형진  ;  하정옥  ;  신희영  ;  임현선 
 Clinical Pediatric Hematology-Oncology (임상소아혈액종양), Vol.14(2) : 167-175, 2007 
Journal Title
 Clinical Pediatric Hematology-Oncology (임상소아혈액종양) 
Issue Date
Purpose: Medulloblastoma is the most common primary malignant brain tumor of childhood. In spite of improved multimodality approach, 30∼40% of children with medulloblastoma still suffer from recurrence. Furthermore, many survivors have significant long-term sequelae. This study was undertaken to investigate the current status of childhood medulloblastoma in Korea. Methods: Questionnaires were sent to the member hospitals of the Korean Society of Pediatric Neuro-Oncology. One hundred and sixty seven cases from 20 university hospitals were collected and analyzed. Results: The median age at diagnosis was 6.9 years and the male to female ratio was 1.9:1. Patients in average risk group were 77 (46%) and those in high risk group were 90 (54%). In average risk group, 1 patient was treated with operation only, 4 were treated with operation and radiotherapy, 70 were treated with operation, radiotherapy and chemotherapy, 2 were treated with various treatments. In high risk group, 4 patients were treated with operation and radiotherapy, 9 were treated with operation and chemotherapy, 58 were treated with operation, radiotherapy and chemotherapy, 16 were treated with high dose chemotherapy and autologous stem cell rescue, and 3 were treated with various treatments. Median follow up was at 30.8 months, and 3 year EFS was 65% for all patients. The 3 year EFS were 78% for patients in average risk group and 54% for patients in high risk group. Conclusion: Diverse treatment protocols have been applied for childhood medulloblastoma in Korea. This study inspired the necessity of nation-wide protocols and prospective multicenter studies for medulloblastoma in Korea.
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1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Lyu, Chuhl Joo(유철주) ORCID logo https://orcid.org/0000-0001-7124-7818
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