3 229

Cited 0 times in

성인 T-세포 백혈병/림프종 1예

Other Titles
 A Case of Adult T-cell Leukemia/Lymphoma 
Authors
 정진영  ;  이희정  ;  이광훈  ;  이주희 
Citation
 Korean Journal of Dermatology (대한피부과학회지), Vol.45(1) : 58-62, 2007 
Journal Title
 Korean Journal of Dermatology (대한피부과학회지) 
ISSN
 1225-8180 
Issue Date
2007
Abstract
Adult T-cell leukemia/lymphoma (ATLL) is a human malignancy associated with human T-cell leukemia virus type I (HTLV-I), which frequently involves the skin. ATLL can be diagnosed based on clinicopathological findings and the presence of anti-HTLV-I serum antibodies and monoclonal integrated HTLV-I provirus in the DNA of tumor cells. It is characterized by leukemia, lymphadenopathy, hypercalcemia, and lytic bone lesions. We report a case of ATLL in a 59-year-old man who developed multiple, scattered papules on the face and trunk. He had a 3-month history of melena. The physical examination showed multiple cervical and axillary lymph node enlargements. On laboratory investigation, the white blood cell count was 113,900/mm3 with 70% atypical lymphocytes. Histopathological and immunohistochemical analyses of a skin and stomach biopsy confirmed the diagnosis of T-cell lymphoma. Final diagnosis of ATLL was made based on HTLV-I positivity. The patient underwent multiple cycles of combination chemotherapy and combination therapy of zidovudine and interferon-α which produced some improvement, but he died of pulmonary complications 3 months after the initial diagnosis.
Full Text
http://kiss.kstudy.com/journal/thesis_name.asp?tname=kiss2002&key=2596122
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Kwang Hoon(이광훈)
Lee, Ju Hee(이주희) ORCID logo https://orcid.org/0000-0002-1739-5956
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96874
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse