Cited 77 times in
Patterning the size and number of tooth and its cusps
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김재영 | - |
dc.contributor.author | 이민정 | - |
dc.contributor.author | 정한성 | - |
dc.contributor.author | 조성원 | - |
dc.date.accessioned | 2014-12-21T16:34:21Z | - |
dc.date.available | 2014-12-21T16:34:21Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0012-1606 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95939 | - |
dc.description.abstract | Mice and rats, two species of rodents, show some dental similarities such as tooth number and cusp number, and differences such as tooth size and cusp size. In this study, the tooth size, tooth number, cusp size and cusp number, which are four major factors of the tooth patterning, were investigated by the heterospecific recombinations of tissues from the molar tooth germs of mice and rats. Our results suggest that the dental epithelium and mesenchyme determine the cusp size and tooth size respectively and the cusp number is co-regulated by the tooth size and cusp size. It is also suggested that the mesenchymal cell number regulates not the tooth size but the tooth number. The relationships among these factors in tooth patterning including micropatterning (cusp size and cusp number) and macropatterning (tooth size and tooth number) were analyzed in a reaction diffusion mechanism. Key molecules determining the patterning of teeth remains to be elucidated for controlling the tooth size and cusp size of bioengineered tooth. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 499~507 | - |
dc.relation.isPartOf | DEVELOPMENTAL BIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Body Patterning | - |
dc.subject.MESH | Epithelium/embryology | - |
dc.subject.MESH | Epithelium/growth & development | - |
dc.subject.MESH | Mandible/embryology* | - |
dc.subject.MESH | Mandible/growth & development | - |
dc.subject.MESH | Mesoderm/cytology | - |
dc.subject.MESH | Mice | - |
dc.subject.MESH | Mice, Inbred ICR | - |
dc.subject.MESH | Mice, Nude | - |
dc.subject.MESH | Molar/embryology | - |
dc.subject.MESH | Molar/growth & development | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Species Specificity | - |
dc.subject.MESH | Tooth/anatomy & histology | - |
dc.subject.MESH | Tooth/embryology* | - |
dc.subject.MESH | Tooth/growth & development | - |
dc.title | Patterning the size and number of tooth and its cusps | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학) | - |
dc.contributor.googleauthor | Jinglei Cai | - |
dc.contributor.googleauthor | Sung-Won Cho | - |
dc.contributor.googleauthor | Han-Sung Jung | - |
dc.contributor.googleauthor | Yoon-Geun Cha | - |
dc.contributor.googleauthor | Min-Jung Lee | - |
dc.contributor.googleauthor | Jae-Young Kim | - |
dc.identifier.doi | 10.1016/j.ydbio.2007.01.002 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03758 | - |
dc.contributor.localId | A03837 | - |
dc.contributor.localId | A00862 | - |
dc.contributor.localId | A02785 | - |
dc.relation.journalcode | J00713 | - |
dc.identifier.eissn | 1095-564X | - |
dc.identifier.pmid | 17289014 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0012160607000164 | - |
dc.contributor.alternativeName | Kim, Jae Young | - |
dc.contributor.alternativeName | Lee, Min Jung | - |
dc.contributor.alternativeName | Jung, Han Sung | - |
dc.contributor.alternativeName | Cho, Sung Won | - |
dc.contributor.affiliatedAuthor | Jung, Han Sung | - |
dc.contributor.affiliatedAuthor | Cho, Sung Won | - |
dc.contributor.affiliatedAuthor | Kim, Jae Young | - |
dc.contributor.affiliatedAuthor | Lee, Min Jung | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 304 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 499 | - |
dc.citation.endPage | 507 | - |
dc.identifier.bibliographicCitation | DEVELOPMENTAL BIOLOGY, Vol.304(2) : 499-507, 2007 | - |
dc.identifier.rimsid | 35317 | - |
dc.type.rims | ART | - |
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