Cited 21 times in
Cross-allergenicity of pollens from the Compositae family: Artemisia vulgaris, Dendranthema grandiflorum, and Taraxacum officinale
DC Field | Value | Language |
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dc.contributor.author | 박중원 | - |
dc.contributor.author | 손정호 | - |
dc.contributor.author | 이용원 | - |
dc.contributor.author | 최수영 | - |
dc.contributor.author | 홍천수 | - |
dc.date.accessioned | 2014-12-21T16:23:29Z | - |
dc.date.available | 2014-12-21T16:23:29Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1081-1206 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95604 | - |
dc.description.abstract | BACKGROUND: Chrysanthemum, dandelion, and mugwort belong to the Compositae (Asteraceae) family. Their cross-allergenicity has not yet been completely evaluated. OBJECTIVE: To investigate the sensitization and cross-allergenicity of these 3 plants. METHODS: We reviewed 6,497 respiratory allergic patients who underwent skin prick tests (SPTs) during the last 10 years (1995-2005) and analyzed the sensitization rates of the 3 pollens. We sorted this population by wheal size and selected the monosensitized or cosensitized patients. Their serum samples were used to evaluate specific IgE (sIgE) and cross-allergenicity of the 3 pollens by CAP, immunoblotting, and inhibition enzyme-linked immunosorbent assay (ELISA). RESULTS: On SPTs, mugwort, chrysanthemum, and dandelion sensitized 13.4%, 10.0%, and 8.5% of the enrolled population, respectively, and 5.2% of the population was cosensitized to all 3 pollens. Some patients were monosensitized to 1 species (1.5% to chrysanthemum, 1.4% to dandelion, and 4.5% to mugwort). In inhibition ELISA that used a pooled serum sample cosensitized to all 3 pollens, mugwort inhibited sIgE bindings to chrysanthemum, dandelion, and mugwort up to 95%, 86%, and 96%, respectively. The 50% inhibitory allergen concentrations for sIgE to each of the 3 species were not different between solid-phase antigen and mugwort. The mugwort sIgE of this pooled serum was suppressed up to 74% and 27% by chrysanthemum and dandelion, respectively. The 50% inhibitory allergen concentrations of chrysanthemum and dandelion for mugwort sIgE were 0.3 and 57.0 microg/mL, respectively, whereas that of mugwort was 0.05 microg/mL. We found a patient who was truly monosensitized to dandelion. CONCLUSION: Chrysanthemum and dandelion were frequently cosensitized with mugwort in the general population with respiratory allergic diseases. These 2 species also showed extensive cross-allergenicity with mugwort. True monosensitization to these 2 species was possible. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 526~533 | - |
dc.relation.isPartOf | ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Cross-allergenicity of pollens from the Compositae family: Artemisia vulgaris, Dendranthema grandiflorum, and Taraxacum officinale | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Yong Won Lee | - |
dc.contributor.googleauthor | Soo Young Cho | - |
dc.contributor.googleauthor | Chein-Soo Hong | - |
dc.contributor.googleauthor | Jung-Won Park | - |
dc.contributor.googleauthor | Jung Ho Sohn | - |
dc.contributor.googleauthor | Eun Kyung Lee | - |
dc.identifier.doi | 10.1016/S1081-1206(10)60382-1 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01681 | - |
dc.contributor.localId | A01993 | - |
dc.contributor.localId | A02981 | - |
dc.contributor.localId | A04093 | - |
dc.contributor.localId | A04448-1 | - |
dc.relation.journalcode | J00153 | - |
dc.identifier.eissn | 1534-4436 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1081120610603821 | - |
dc.contributor.alternativeName | Park, Jung Won | - |
dc.contributor.alternativeName | Sohn, Jung Ho | - |
dc.contributor.alternativeName | Lee, Yong Won | - |
dc.contributor.alternativeName | Choi, Soo Young | - |
dc.contributor.alternativeName | Hong, Chein Soo | - |
dc.contributor.affiliatedAuthor | Park, Jung Won | - |
dc.contributor.affiliatedAuthor | Sohn, Jung Ho | - |
dc.contributor.affiliatedAuthor | Lee, Yong Won | - |
dc.contributor.affiliatedAuthor | Choi, Soo Young | - |
dc.contributor.affiliatedAuthor | Hong, Chein Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 99 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 526 | - |
dc.citation.endPage | 533 | - |
dc.identifier.bibliographicCitation | ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, Vol.99(6) : 526-533, 2007 | - |
dc.identifier.rimsid | 44960 | - |
dc.type.rims | ART | - |
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