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Cytologic characteristics of subependymal giant cell astrocytoma in squash smears: Morphometric comparisons with gemistocytic astrocytoma and giant cell glioblastoma

Authors
 Kim S.H.  ;  Lee K.  ;  Kim T.S 
Citation
 ACTA CYTOLOGICA, Vol.51(3) : 375-379, 2007 
Journal Title
ACTA CYTOLOGICA
ISSN
 0001-5547 
Issue Date
2007
Abstract
OBJECTIVE:
To evaluate the squash smear features of subependymal giant cell astrocytoma (SEGA) in comparison with gemistocytic astrocytoma and giant cell glioblastoma.
STUDY DESIGN:
We compared the squash smear features of 3 cases of SEGA, 9 cases of gemistocytic astrocytoma and 3 cases of giant cell glioblastoma with the morphometric findings.
RESULTS:
SEGA had, on average, a 15.84 +/- 5.03-microm nucleus, 33.22 +/- 12.05-microm cytoplasm and 0.50 +/- 0.12 nuclear/cytoplasmic ratio in squash smears. In addition, SEGA showed hairlike processes distributed along the squash direction like strap cells. While the gemistocytic astrocytoma had several tumor cells showing a vertically located nucleus, the tumor cells of SEGA showed nuclei oriented mainly in parallel.
CONCLUSION:
These squash cytologic features of SEGA can be very helpful in the differential diagnosis by excluding mimics.
Full Text
http://www.karger.com/Article/Abstract/325750
DOI
10.1159/000325750
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Se Hoon(김세훈) ORCID logo https://orcid.org/0000-0001-7516-7372
Kim, Tai Seung(김태승)
Lee, Kwang Gill(이광길)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95507
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