0 448

Cited 0 times in

Nucleic acid therapy for lifespan prolongation: present and future

DC Field Value Language
dc.contributor.author여영부-
dc.date.accessioned2014-12-20T17:53:57Z-
dc.date.available2014-12-20T17:53:57Z-
dc.date.issued2011-
dc.identifier.issn0250-5991-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/95465-
dc.description.abstractLifespan prolongation is a common desire of the human race. With advances in biotechnology, the mechanism of aging has been gradually unraveled, laying the theoretical basis of nucleic acid therapy for lifespan prolongation. Regretfully, clinically applicable interventions do not exist without the efforts of converting theory into action, and it is the latter that has been far from adequately addressed at the moment. This was demonstrated by a database search on PubMed and Web of Science, from which only seven studies published between 2000 and 2010 were found to directly touch on the development of nucleic acid therapy for anti-aging and/or longevity enhancing purposes. In light of this, the objective of this article is to overview the current understanding of the intimate association between genes and longevity, and to bring the prospect of nucleic acid therapy for lifespan prolongation to light.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJOURNAL OF BIOSCIENCES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHBibliography as Topic-
dc.subject.MESHCaenorhabditis elegans-
dc.subject.MESHDrosophila melanogaster-
dc.subject.MESHForecasting-
dc.subject.MESHHumans-
dc.subject.MESHLife Expectancy-
dc.subject.MESHLongevity*/drug effects-
dc.subject.MESHLongevity*/genetics-
dc.subject.MESHMice-
dc.subject.MESHNucleic Acids*/pharmacology-
dc.subject.MESHNucleic Acids*/therapeutic use-
dc.subject.MESHSignal Transduction-
dc.subject.MESHYeasts-
dc.titleNucleic acid therapy for lifespan prolongation: present and future-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Biology (구강생물학)-
dc.contributor.googleauthorWING-FU LAI-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02347-
dc.relation.journalcodeJ01272-
dc.identifier.eissn0973-7138-
dc.identifier.pmid21857119-
dc.identifier.urlhttps://link.springer.com/article/10.1007/s12038-011-9096-z-
dc.subject.keywordAging-
dc.subject.keywordgenes-
dc.subject.keywordlifespan-
dc.subject.keywordlongevity-
dc.subject.keywordnucleic acid therapy-
dc.contributor.alternativeNameLai, Wing Fu-
dc.contributor.affiliatedAuthorLai, Wing Fu-
dc.citation.volume36-
dc.citation.number4-
dc.citation.startPage725-
dc.citation.endPage729-
dc.identifier.bibliographicCitationJOURNAL OF BIOSCIENCES, Vol.36(4) : 725-729, 2011-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.