Cited 17 times in
The humoral immune response to the inactivated influenza A (H1N1) 2009 monovalent vaccine in patients with Type 2 diabetes mellitus in Korea.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김아름 | - |
dc.contributor.author | 남지선 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 윤주천 | - |
dc.contributor.author | 이재면 | - |
dc.contributor.author | 조상래 | - |
dc.contributor.author | 김경래 | - |
dc.date.accessioned | 2014-12-20T17:52:56Z | - |
dc.date.available | 2014-12-20T17:52:56Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0742-3071 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95434 | - |
dc.description.abstract | AIMS: We evaluated the antibody response to a single-dose adjuvanted, inactivated, pandemic H1N1 influenza vaccination in patients with diabetes and assessed factors associated with the failure to induce antibody responses. METHODS: Eighty-two patients with Type 2 diabetes were vaccinated and antibody responses were determined with haemagglutination inhibition assay and anti-haemagglutinin antibody ELISA. RESULTS: Among 70 antibody-negative patients at baseline, 34 (48.6%) achieved seroconversion; 28 (60.9%) in the young adults group and six (25%) in the elderly group acquired H1N1-specific antibodies. Patients in the older age range or with longer duration of diabetes had a lower seroconversion rate. CONCLUSIONS: Our data show low cross-reactive antibody carrying rate and low seroconversion rate in patients with diabetes. Until larger-scale, case-controlled trials become available, older patients and patients with a longer duration of diabetes should be considered for the two-dose vaccination or have antibody titres measured after the first vaccination. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 815~817 | - |
dc.relation.isPartOf | DIABETIC MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Antibodies, Viral/immunology | - |
dc.subject.MESH | Antibody Formation/immunology | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/complications | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/epidemiology | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/immunology* | - |
dc.subject.MESH | Enzyme-Linked Immunosorbent Assay | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunity, Humoral | - |
dc.subject.MESH | Influenza A Virus, H1N1 Subtype/immunology* | - |
dc.subject.MESH | Influenza Vaccines/immunology* | - |
dc.subject.MESH | Influenza, Human/epidemiology | - |
dc.subject.MESH | Influenza, Human/prevention & control* | - |
dc.subject.MESH | Korea/epidemiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Young Adult | - |
dc.title | The humoral immune response to the inactivated influenza A (H1N1) 2009 monovalent vaccine in patients with Type 2 diabetes mellitus in Korea. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | J. S. Nam | - |
dc.contributor.googleauthor | A. R. Kim | - |
dc.contributor.googleauthor | J. C. Yoon | - |
dc.contributor.googleauthor | Y. Byun | - |
dc.contributor.googleauthor | S. A. Kim | - |
dc.contributor.googleauthor | K. R. Kim | - |
dc.contributor.googleauthor | S. Cho | - |
dc.contributor.googleauthor | B. L. Seong | - |
dc.contributor.googleauthor | C. W. Ahn | - |
dc.contributor.googleauthor | J. M. Lee | - |
dc.identifier.doi | 10.1111/j.1464-5491.2011.03255.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00679 | - |
dc.contributor.localId | A01268 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A02603 | - |
dc.contributor.localId | A03071 | - |
dc.contributor.localId | A03824 | - |
dc.contributor.localId | A00294 | - |
dc.relation.journalcode | J00726 | - |
dc.identifier.eissn | 1464-5491 | - |
dc.identifier.pmid | 21672004 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2011.03255.x/abstract | - |
dc.subject.keyword | antibody seroconversion | - |
dc.subject.keyword | influenza A (H1N1) | - |
dc.subject.keyword | 2009 monovalent vaccine | - |
dc.subject.keyword | Type 2 diabetes mellitus | - |
dc.contributor.alternativeName | Kim, Ah Reum | - |
dc.contributor.alternativeName | Nam, Ji Sun | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Yoon, Joo Chun | - |
dc.contributor.alternativeName | Lee, Jae Myun | - |
dc.contributor.alternativeName | Cho, Sang Nae | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.affiliatedAuthor | Kim, Ah Reum | - |
dc.contributor.affiliatedAuthor | Nam, Ji Sun | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Yoon, Joo Chun | - |
dc.contributor.affiliatedAuthor | Lee, Jae Myun | - |
dc.contributor.affiliatedAuthor | Cho, Sang Nae | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Rae | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 28 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 815 | - |
dc.citation.endPage | 817 | - |
dc.identifier.bibliographicCitation | DIABETIC MEDICINE, Vol.28(7) : 815-817, 2011 | - |
dc.identifier.rimsid | 40816 | - |
dc.type.rims | ART | - |
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