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The humoral immune response to the inactivated influenza A (H1N1) 2009 monovalent vaccine in patients with Type 2 diabetes mellitus in Korea.

DC FieldValueLanguage
dc.contributor.author김아름-
dc.contributor.author남지선-
dc.contributor.author안철우-
dc.contributor.author윤주천-
dc.contributor.author이재면-
dc.contributor.author조상래-
dc.contributor.author김경래-
dc.date.accessioned2014-12-20T17:52:56Z-
dc.date.available2014-12-20T17:52:56Z-
dc.date.issued2011-
dc.identifier.issn0742-3071-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/95434-
dc.description.abstractAIMS: We evaluated the antibody response to a single-dose adjuvanted, inactivated, pandemic H1N1 influenza vaccination in patients with diabetes and assessed factors associated with the failure to induce antibody responses. METHODS: Eighty-two patients with Type 2 diabetes were vaccinated and antibody responses were determined with haemagglutination inhibition assay and anti-haemagglutinin antibody ELISA. RESULTS: Among 70 antibody-negative patients at baseline, 34 (48.6%) achieved seroconversion; 28 (60.9%) in the young adults group and six (25%) in the elderly group acquired H1N1-specific antibodies. Patients in the older age range or with longer duration of diabetes had a lower seroconversion rate. CONCLUSIONS: Our data show low cross-reactive antibody carrying rate and low seroconversion rate in patients with diabetes. Until larger-scale, case-controlled trials become available, older patients and patients with a longer duration of diabetes should be considered for the two-dose vaccination or have antibody titres measured after the first vaccination.-
dc.description.statementOfResponsibilityopen-
dc.format.extent815~817-
dc.relation.isPartOfDIABETIC MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAntibodies, Viral/immunology-
dc.subject.MESHAntibody Formation/immunology-
dc.subject.MESHDiabetes Mellitus, Type 2/complications-
dc.subject.MESHDiabetes Mellitus, Type 2/epidemiology-
dc.subject.MESHDiabetes Mellitus, Type 2/immunology*-
dc.subject.MESHEnzyme-Linked Immunosorbent Assay-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImmunity, Humoral-
dc.subject.MESHInfluenza A Virus, H1N1 Subtype/immunology*-
dc.subject.MESHInfluenza Vaccines/immunology*-
dc.subject.MESHInfluenza, Human/epidemiology-
dc.subject.MESHInfluenza, Human/prevention & control*-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRisk Factors-
dc.subject.MESHYoung Adult-
dc.titleThe humoral immune response to the inactivated influenza A (H1N1) 2009 monovalent vaccine in patients with Type 2 diabetes mellitus in Korea.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJ. S. Nam-
dc.contributor.googleauthorA. R. Kim-
dc.contributor.googleauthorJ. C. Yoon-
dc.contributor.googleauthorY. Byun-
dc.contributor.googleauthorS. A. Kim-
dc.contributor.googleauthorK. R. Kim-
dc.contributor.googleauthorS. Cho-
dc.contributor.googleauthorB. L. Seong-
dc.contributor.googleauthorC. W. Ahn-
dc.contributor.googleauthorJ. M. Lee-
dc.identifier.doi10.1111/j.1464-5491.2011.03255.x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00679-
dc.contributor.localIdA01268-
dc.contributor.localIdA02270-
dc.contributor.localIdA02603-
dc.contributor.localIdA03071-
dc.contributor.localIdA03824-
dc.contributor.localIdA00294-
dc.relation.journalcodeJ00726-
dc.identifier.eissn1464-5491-
dc.identifier.pmid21672004-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2011.03255.x/abstract-
dc.subject.keywordantibody seroconversion-
dc.subject.keywordinfluenza A (H1N1)-
dc.subject.keyword2009 monovalent vaccine-
dc.subject.keywordType 2 diabetes mellitus-
dc.contributor.alternativeNameKim, Ah Reum-
dc.contributor.alternativeNameNam, Ji Sun-
dc.contributor.alternativeNameAhn, Chul Woo-
dc.contributor.alternativeNameYoon, Joo Chun-
dc.contributor.alternativeNameLee, Jae Myun-
dc.contributor.alternativeNameCho, Sang Nae-
dc.contributor.alternativeNameKim, Kyung Rae-
dc.contributor.affiliatedAuthorKim, Ah Reum-
dc.contributor.affiliatedAuthorNam, Ji Sun-
dc.contributor.affiliatedAuthorAhn, Chul Woo-
dc.contributor.affiliatedAuthorYoon, Joo Chun-
dc.contributor.affiliatedAuthorLee, Jae Myun-
dc.contributor.affiliatedAuthorCho, Sang Nae-
dc.contributor.affiliatedAuthorKim, Kyung Rae-
dc.rights.accessRightsnot free-
dc.citation.volume28-
dc.citation.number7-
dc.citation.startPage815-
dc.citation.endPage817-
dc.identifier.bibliographicCitationDIABETIC MEDICINE, Vol.28(7) : 815-817, 2011-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Microbiology (미생물학교실) > 1. Journal Papers

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