Cited 57 times in
Antiplatelet and anticoagulation therapy in vitreoretinal surgery.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김성수 | - |
dc.date.accessioned | 2014-12-20T17:50:30Z | - |
dc.date.available | 2014-12-20T17:50:30Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0002-9394 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95356 | - |
dc.description.abstract | PURPOSE: To evaluate changes in the prevalence of antiplatelet (aspirin, clopidogrel) and anticoagulation (warfarin) therapy and its possible relationship to postoperative bleeding in vitreoretinal surgery (VRS) patients. DESIGN: Observational, retrospective case control study. METHODS: setting: University practice.study population: A total of 822 patents who underwent VRS during 3 intervals in 1994, 2004, and 2008.observation procedure: Retrospective chart review for 1994 and 2004, but contemporaneous in 2008.main outcome measures: Proportion using antiplatelets or anticoagulants, the incidence of early postoperative intraocular bleeding in patients, and clinical consequence of the hemorrhage. RESULTS: Thirty-one of 213 patients (14.6%) who underwent VRS in 1994, 103 of 361 patients (28.5%) in 2004, and 80 of 248 patients (32.3%) in 2008 had taken antiplatelet therapy (P < .001). The rates of anticoagulant therapy did not vary. The incidence of bleeding was higher (20.0%) in the patients who did not suspend antiplatelets than in those who did (9.6%) (P = .05, χ(2) test), but this difference lost statistical significance in a multivariate analysis (P = .079). Anticoagulant was associated with intraocular hemorrhage at postoperative first day after vitrectomy (P = .03, Fisher exact test). No reoperation or failure of the surgery was attributable to the hemorrhage in anticoagulant or antiplatelet patients. CONCLUSIONS: Use of antiplatelet agents has increased in patients undergoing vitreoretinal surgery but probably does not increase the risk of postoperative intraocular bleeding; however, when safe to suspend even for a short time the potential risk is further reduced. Anticoagulant use was associated with a higher risk, but without serious consequences. Working with a patient's medical doctor may allow safe suspension in some cases, which may further lower these risks. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF OPHTHALMOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Anticoagulants/therapeutic use* | - |
dc.subject.MESH | Aspirin/therapeutic use | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Contraindications | - |
dc.subject.MESH | Eye Hemorrhage/chemically induced | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Platelet Aggregation Inhibitors/therapeutic use* | - |
dc.subject.MESH | Postoperative Hemorrhage* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Ticlopidine/analogs & derivatives | - |
dc.subject.MESH | Ticlopidine/therapeutic use | - |
dc.subject.MESH | Vitreoretinal Surgery* | - |
dc.subject.MESH | Warfarin/therapeutic use | - |
dc.title | Antiplatelet and anticoagulation therapy in vitreoretinal surgery. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Jaeryung Oh | - |
dc.contributor.googleauthor | William E. Smiddy | - |
dc.contributor.googleauthor | Sung Soo Kim | - |
dc.identifier.doi | 10.1016/j.ajo.2010.09.035 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00571 | - |
dc.relation.journalcode | J00097 | - |
dc.identifier.eissn | 1879-1891 | - |
dc.identifier.pmid | 21411057 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S000293941000961X | - |
dc.contributor.alternativeName | Kim, Sung Soo | - |
dc.contributor.affiliatedAuthor | Kim, Sung Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 151 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 934 | - |
dc.citation.endPage | 939.e3 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF OPHTHALMOLOGY, Vol.151(6) : 934-939.e3, 2011 | - |
dc.identifier.rimsid | 48317 | - |
dc.type.rims | ART | - |
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