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The impact of body mass index on pancreatic fistula after pancreaticoduodenectomy in Asian patients on the basis of Asia-Pacific perspective of body mass index

 Ho Kyoung Hwang  ;  Joon Seong Park  ;  Chan-il Park  ;  Jae Keun Kim  ;  Dong Sup Yoon 
 JOURNAL OF THE PANCREAS, Vol.12(6) : 586-592, 2011 
Journal Title
Issue Date
Aged ; Asia/epidemiology ; Asian Continental Ancestry Group/statistics & numerical data* ; Body Mass Index* ; Female ; Gastric Emptying/physiology ; Humans ; Male ; Middle Aged ; Obesity/complications ; Obesity/epidemiology ; Pacific Ocean ; Pancreatic Fistula/epidemiology ; Pancreatic Fistula/ethnology ; Pancreatic Fistula/etiology* ; Pancreatic Fistula/surgery ; Pancreaticoduodenectomy/adverse effects* ; Pancreaticoduodenectomy/statistics & numerical data ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Retrospective Studies
Body Mass Index ; Obesity ; Pancreatic Fistula ; Pancreaticoduodenectomy
CONTEXT: Several surgical complications are related to obesity.

OBJECTIVE: This study evaluated the impact of obesity on pancreatic fistula after pancreaticoduodenectomy.

DESIGN: We retrospectively reviewed the medical records of 159 patients who underwent pancreaticoduodenectomy between October 2002 and December 2008.

SETTING: The patients were divided according to the body mass index as obese (body mass index equal to, or greater than, 25 kg/m(2)), or normal (body mass index less than 25 kg/m(2)).

METHODS: Univariate and multivariate analyses were applied. Two-tailed P values less than 0.05 were considered as significant.

RESULTS: Forty-six patients (28.9%) were obese and 113 patients (71.1%) were normal-weight. Obese group had a significantly higher incidence of pancreatic fistula and a greater amount of intraoperative blood loss. Other surgical complications were not significantly different between the two groups. Multivariate analysis found obesity, small pancreatic duct size (less than, or equal to, 3 mm), intraoperative blood loss, and combined resection as significant factors affecting pancreatic fistula.

CONCLUSIONS: Obese patients have an increased risk for pancreatic fistula after pancreaticoduodenectomy.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Keun(김재근)
Park, Joon Seong(박준성) ORCID logo https://orcid.org/0000-0001-8048-9990
Park, Chan Il(박찬일)
Yoon, Dong Sup(윤동섭) ORCID logo https://orcid.org/0000-0001-6444-9606
Hwang, Ho Kyoung(황호경) ORCID logo https://orcid.org/0000-0003-4064-7776
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