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Antibacterial effect and cytocompatibility of nano-structured TiO(2) film containing Cl.

Authors
 Min-Kyung KANG  ;  Seung-Kyun MOON  ;  Kwang-Mahn KIM  ;  Kyoung-Nam KIM 
Citation
 DENTAL MATERIALS JOURNAL, Vol.30(6) : 790-798, 2011 
Journal Title
DENTAL MATERIALS JOURNAL
ISSN
 0287-4547 
Issue Date
2011
MeSH
Anti-Bacterial Agents/chemistry* ; Anti-Bacterial Agents/pharmacology ; Bacterial Adhesion/drug effects* ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dental Implants* ; Humans ; Materials Testing* ; Microbial Sensitivity Tests ; Osteoblasts/drug effects ; Sodium Chloride/chemistry ; Streptococcus mutans/drug effects* ; Surface Properties ; Titanium/adverse effects ; Titanium/chemistry* ; Titanium/pharmacology ; Wettability
Keywords
Antibacterial effect ; Cl ; Nano ; TiO2
Abstract
The aim of this study was to investigate the antibacterial effect and cytocompatibility of a nano-structured TiO(2) film that contained Cl and had been coated onto commercially pure titanium. First, we prepared nano-structured TiO(2) by anodization with hydrofluoric acid. Then, to confer an antibacterial effect, we performed a second anodization with NaCl solutions of different concentrations (0.5 M, 1 M, 2 M). The morphology, composition, and wettability of the surface were investigated by SEM, EDS, and a video contact angle measuring system. The antibacterial effect was evaluated by film adhesion method. And cytotoxicity was determined by the viability of MG-63 cells in a MTT assay. The SEM and EDS results showed that the TiO(2) nano-structure containing Cl had successfully formed after the second anodization. The contact angle analysis showed that the anodized titanium had a hydrophilic character. The results of this in vitro investigation demonstrated that the TiO(2) nano-structure film anodized in 1 M NaCl had an antibacterial effect and good cell compatibility
Files in This Item:
T201105169.pdf Download
DOI
10.4012/dmj.2011-021
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kang, Min Kyung(강민경)
Kim, Kyoung Nam(김경남)
Kim, Kwang Mahn(김광만) ORCID logo https://orcid.org/0000-0002-5235-0294
Moon, Seung Kyun(문승균)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95023
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