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New index for categorising cardiac reentrant wave: in silico evaluation

Authors
 E.B. Shim  ;  S.-B. Hong  ;  D. Noble  ;  Y.E. Earm  ;  H.-N. Pak  ;  C.-H. Youn  ;  C.H. Leem  ;  K.M. Lim 
Citation
 IET Sytems Biology, Vol.5(5) : 317-323, 2011 
Journal Title
 IET Sytems Biology 
ISSN
 1751-8849 
Issue Date
2011
Abstract
Based on the similarity between a reentrant wave in cardiac tissue and a vortex in fluid dynamics, the authors hypothesised that a new non-dimensional index, like the Reynolds number in fluid dynamics, may play a critical role in categorising reentrant wave dynamics. Therefore the goal of the present study is to devise a new index to characterise electric wave conduction in cardiac tissue and examined whether this index can be used as a biomarker for categorising the reentrant wave pattern in cardiac tissue. Similar to the procedure used to derive the Reynolds number in fluid dynamics, the authors used a non-dimensionalisation technique to obtain the new index. Its usefulness was verified using a two-dimensional simulation model of electrical wave propagation in cardiac tissue. The simulation results showed that electrical waves in cardiac tissue move into an unstable region when the index exceeds a threshold value.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94967
DOI
10.1049/iet-syb.2011.0019
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
박희남(Pak, Hui Nam)
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Full Text
http://digital-library.theiet.org/content/journals/10.1049/iet-syb.2011.0019
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